Monday, 26 December 2011

Spironolactone Teva




Spironolactone Teva may be available in the countries listed below.


Ingredient matches for Spironolactone Teva



Spironolactone

Spironolactone is reported as an ingredient of Spironolactone Teva in the following countries:


  • France

International Drug Name Search

Mercaptyl




Mercaptyl may be available in the countries listed below.


Ingredient matches for Mercaptyl



Penicillamine

Penicillamine is reported as an ingredient of Mercaptyl in the following countries:


  • Switzerland

International Drug Name Search

Friday, 23 December 2011

Etanercept




In the US, Etanercept (etanercept systemic) is a member of the following drug classes: antirheumatics, TNF alfa inhibitors and is used to treat Ankylosing Spondylitis, Behcet's Disease, Bullous Pemphigoid, Cogan's Syndrome, Histiocytosis, Juvenile Idiopathic Arthritis, Juvenile Rheumatoid Arthritis, Macrophage Activation Syndrome, Pemphigoid, Pemphigus, Psoriasis, Psoriatic Arthritis, Rheumatoid Arthritis, SAPHO Syndrome, Still's Disease, Uveitis and Wegener's Granulomatosus.

US matches:

  • Etanercept

  • Etanercept Subcutaneous

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L04AA11,L04AB01

CAS registry number (Chemical Abstracts Service)

0185243-69-0

Chemical Formula

C2224-H3472-N618-O701-S36

Molecular Weight

51238

Therapeutic Categories

Immunosuppressant

Anti-inflammatory agent

Disease-modifying antirheumatic drug, DMARD

Biological response modifier, BRM

Tumor necrosis factor alpha (TNF-α) inhibitor

Chemical Name

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1

Foreign Names

  • Etanerceptum (Latin)
  • Etanercept (German)
  • Étanercept (French)
  • Etanercept (Spanish)

Generic Names

  • Etanercept (OS: USAN, BAN)
  • Étanercept (OS: DCF)
  • rhu TNFR:Fc (IS)
  • TNF receptor p75 fusion protein (IS)

Brand Names

  • Enbrel Myclic
    Wyeth, Germany


  • Enbrel
    Amgen, Canada; Amgen, United States; Pfizer, Switzerland; PharmaSwiss, Croatia (Hrvatska); Wyeth, Argentina; Wyeth, Austria; Wyeth, Australia; Wyeth, Belgium; Wyeth, Bahrain; Wyeth, Brazil; Wyeth, Chile; Wyeth, Colombia; Wyeth, Costa Rica; Wyeth, Czech Republic; Wyeth, Germany; Wyeth, Denmark; Wyeth, Spain; Wyeth, Finland; Wyeth, France; Wyeth, Greece; Wyeth, Guatemala; Wyeth, Hong Kong; Wyeth, Honduras; Wyeth, Hungary; Wyeth, Ireland; Wyeth, Israel; Wyeth, India; Wyeth, Iceland; Wyeth, Italy; Wyeth, Luxembourg; Wyeth, Mexico; Wyeth, Malaysia; Wyeth, Nicaragua; Wyeth, Netherlands; Wyeth, Norway; Wyeth, Oman; Wyeth, Panama; Wyeth, Peru; Wyeth, Philippines; Wyeth, Portugal; Wyeth, Romania; Wyeth, Serbia; Wyeth, Sweden; Wyeth, Singapore; Wyeth, Slovenia; Wyeth, Slovakia; Wyeth, El Salvador; Wyeth, Thailand; Wyeth, Tunisia; Wyeth, Turkey; Wyeth, Taiwan; Wyeth, United States; Wyeth, Venezuela; Wyeth, South Africa; Wyeth Consumer Healthcare, New Zealand; Wyeth KK, Japan; Wyeth Nutrition Internatinoal, Indonesia; Wyeth Pharmaceuticals, United Kingdom


  • Enbrel Junior (pediatric)
    Pfizer, Switzerland


  • Enbrel Pédiatrie (pediatric)
    Wyeth, Belgium

International Drug Name Search

Glossary

BANBritish Approved Name
DCFDénomination Commune Française
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Thursday, 22 December 2011

Fluconazol Ranbaxy




Fluconazol Ranbaxy may be available in the countries listed below.


Ingredient matches for Fluconazol Ranbaxy



Fluconazole

Fluconazole is reported as an ingredient of Fluconazol Ranbaxy in the following countries:


  • Portugal

International Drug Name Search

Tuesday, 20 December 2011

Ejennu




Ejennu may be available in the countries listed below.


Ingredient matches for Ejennu



Cilostazol

Cilostazol is reported as an ingredient of Ejennu in the following countries:


  • Japan

International Drug Name Search

Tuesday, 6 December 2011

Vapresan




Vapresan may be available in the countries listed below.


Ingredient matches for Vapresan



Enalapril

Enalapril maleate (a derivative of Enalapril) is reported as an ingredient of Vapresan in the following countries:


  • Argentina

International Drug Name Search

Monoket retard




Monoket retard may be available in the countries listed below.


Ingredient matches for Monoket retard



Isosorbide Mononitrate

Isosorbide Mononitrate is reported as an ingredient of Monoket retard in the following countries:


  • Austria

International Drug Name Search

Sunday, 4 December 2011

Eltrombopag Olamine




Eltrombopag Olamine may be available in the countries listed below.


Ingredient matches for Eltrombopag Olamine



Eltrombopag

Eltrombopag Olamine (USAN) is known as Eltrombopag in the US.

International Drug Name Search

Glossary

USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Saturday, 3 December 2011

Ermite




Ermite may be available in the countries listed below.


Ingredient matches for Ermite



Permethrin

Permethrin is reported as an ingredient of Ermite in the following countries:


  • Bangladesh

International Drug Name Search

Thursday, 24 November 2011

Terra-Cortil




Terra-Cortil may be available in the countries listed below.


Ingredient matches for Terra-Cortil



Oxytetracycline

Oxytetracycline hydrochloride (a derivative of Oxytetracycline) is reported as an ingredient of Terra-Cortil in the following countries:


  • Finland

  • Peru

International Drug Name Search

Wednesday, 23 November 2011

Brom Mal Phenyl HCl Dex HBr





Dosage Form: liquid

Indications and Usage for Brom Mal Phenyl HCl Dex HBr


Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid is indicated for the temporary relief of symptoms of upper respiratory tract disorders such as nasal congestion, sinusitis, vasomotor rhinitis and hay fever; as well as for the temporary relief of coughs associated with respiratory tract infections and associated conditions such as sinusitis, pharyngitis, bronchitis, and asthma, when these conditions are complicated by tenacious mucus and/or mucus plugs and congestion. Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid is effective in a productive as well as a nonproductive cough, but is of particular value in a dry, nonproductive cough which tends to injure the mucous membrane of the air passages.



DOSAGE AND ADMINISTRATION*


Adults and Children 12 years of age and older: 1 teaspoonful every 4 to 6 hours, not to exceed 6 teaspoonfuls in a 24 hour period.

Children 6 to 12 years of age: 1/2 teaspoonful every 4 to 6 hours, not to exceed 3 teaspoonfuls in a 24 hour period.

Not recommended for children under 6 years of age.

*In mild cases or in particularly sensitive patients, less frequent or reduced doses may be appropriate and adequate.



DOSAGE FORM AND STRENGTH


Oral solution, brompheniramine maleate 4 mg, phenylephrine hydrochloride 7.5 mg, and dextromethorphan hydrobromide 15 mg/5 mL



Contraindications


Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid is contraindicated in patients with a known hypersensitivity to any of the components. Patients known to be hypersensitive to other sympathomimetic amines may exhibit cross sensitivity with phenylephrine. It is also contraindicated in infants and newborns, patients with severe hypertension, severe coronary artery disease, hyperthyroidism, and in patients on MAO inhibitor therapy. Patient idiosyncrasy to adrenergic agents may be manifested by insomnia, dizziness, weakness, tremor, or arrhythmias.



Warnings and Precautions


Do not exceed recommended dosage. Discontinue use if adverse reactions occur.


5.1 General

Before prescribing medication to suppress or modify cough, it is important to ascertain the underlying cause of the cough, that modification of cough does not increase the risk of clinical or physiological complications, and that appropriate therapy for the primary disease is instituted.


5.2 Special Risk Patients

Use with caution in patients with diabetes, hypertension, or cardiovascular disease.


Hypertensive crises can occur with concurrent use of MAO inhibitors (and for 14 days after stopping MAO inhibitor therapy), indomethacin, or with beta-blockers and methyldopa. If a hypertensive crisis occurs, these drugs should be discontinued immediately and therapy to lower blood pressure should be instituted.


Antihistamines have an atropine-like action and therefore should be used with caution in patients with a history of bronchial asthma, increased intraocular pressure, hypothyroidism, cardiovascular disease and hypertension.


Sympathomimetics may produce central nervous system stimulation with convulsions or cardio-vascular collapse with accompanying hypotension. Sympathomimetic amines should be used judiciously and sparingly in patients with hypertension, diabetes mellitus, ischemic heart disease, increased intraocular pressure, hyperthyroidism or prostatic hypertrophy.



Adverse Reactions


Side effects may include drowsiness, dizziness, nervousness, insomnia, headache, palpitation, and dysuria.


To report SUSPECTED ADVERSE REACTIONS, contact FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.



Drug Interactions


Beta-adrenergic blockers and MAO inhibitors may potentiate the pressor effect of phenylephrine. Concurrent use of digitalis glycosides may increase the possibility of cardiac arrhythmias. Sympathomimetics may reduce the hypotensive effects of guanethidine, mecamylamine, methyldopa, reserpine and veratrum alkaloids. Concurrent use of tricyclic antidepressants may antagonize the effects of phenylephrine. Use of other vasopressor drugs during halothane anesthia may cause serious cardiac arrhythmias.



USE IN SPECIFIC POPULATIONS


8.1 Pregnancy

Teratogenic Effects - Pregnancy Category C

It is not known whether this product can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid should be given to a pregnant woman only if clearly needed.


8.3 Nursing Mothers

Small amounts of phenylephrine are excreted in breast milk. Use of this product by nursing mothers is not recommended because of the higher than usual risk for infants from sympathomimetic amines.


8.4 Pediatric Use

Safety and effectiveness in pediatric patients below the age of 6 have not been established.


8.5 Geriatric Use

Elderly patients (60 years of age and older) are more likely to experience adverse reactions to sympathomimetics.



Drug Abuse and Dependence


Central nervous system stimulants have been abused. At high doses, subjects commonly experience an elevation of mood, a sense of increased energy and alertness, and decreased appetite. Some individuals become anxious, irritable, and talk excessively. In addition to the marked euphoria, the user experiences a sense of markedly enhanced physical strength and mental capacity. With continued use, tolerance develops, the user increases the dose, and toxic signs and symptoms appear. Depression may follow rapid withdrawal.


There is no information to indicate that abuse or dependency occurs with guaifenesin or with the combination of guaifenesin, dextromethorphan and phenylephrine.



Overdosage


This product is comprised of three pharmacologically different components. Therefore, it is difficult to predict the exact manifestation of symptoms in a given individual.


10.1 Signs and Symptoms

Dextromethorphan in toxic doses will cause drowsiness, ataxia, nystagmus, opisthotonos and convulsive seizures. Overdosage with sympathomimetic amines can cause cardiac arrhythmias, cerebral hemorrhage and pulmonary edema. It can also cause palpitation, tremor, dizziness, vomiting, fear, labored breathing, headache, dryness of mouth, pallor, weakness, panic, anxiety, confusion, hallucinations, and delirium.


10.2 Treatment

Recommended treatment of acute overdosage would likely be based upon treating the patient for the symptoms of overdosage of phenylephrine. The treatment of overdosage should provide symptomatic and supportive care. If the amount ingested is considered dangerous or excessive, induce vomiting with ipecac syrup unless the patient is convulsing, comatose, or has lost the gag reflex, in which case perform gastric lavage using a large bore tube. If indicated, follow with activated charcoal and a saline cathartic.



Brom Mal Phenyl HCl Dex HBr Description


Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid is an alcohol-free, sugar-free, dye-free, strawberry-flavored, clear liquid.

Each 5 mL (one teaspoonful) for oral administration contains:

Brompheniramine maleate........................................ 4 mg

Phenylephrine hydrochloride ................................. 7.5 mg

Dextromethorphan hydrobromide.............................15 mg


Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid also contains: glycerin, propylene glycol, sorbitol, citric acid, sodium citrate, sodium saccharin, strawberry flavor, purified water.


Brompheniramine Maleate is an antihistamine having the chemical name, 2-Pyridinepropanamine,у-(4-bromophenyl)-N, N-dimethyl-, (±)-,(Z)-2-butenedioate (1:1), with the following structure:



Phenylephrine hydrochloride is an orally effective nasal decongestant. Chemically it is (–)-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride with the following chemical structure:



Dextromethorphan hydrobromide is a salt of the methyl ether of the dextrorotatory isomer of levorphanol, a narcotic analgesic. Chemically, it is 3-methoxy-17-9α, 13α, 14α-morphinan hydrobromide monohydrate and has the following structural formula:




Brom Mal Phenyl HCl Dex HBr - Clinical Pharmacology


12.1 Mechanism of Action

Brompheniramine maleate

Alkylamine-type antihistamines such as brompheniramine maleate are among the most potent H1 blockers and are generally effective in relatively low doses. Although brompheniramine is not as prone as other types of antihistamines to cause drowsiness, a significant proportion of patients do experience this effect. CNS stimulation is more common with alkylamines.


Phenylephrine HCl

Phenylephrine hydrochloride is a sympathomimetic amine which acts predominantly by a direct action on alpha (α) adrenergic receptors. In therapeutic doses, the drug has no significant stimulant effect on the beta (β) adrenergic receptors of the heart. Clinically, phenylephrine shrinks swollen mucous membranes, reduces tissue hyperemia, edema, and nasal congestion; and increases nasal airway patency. In therapeutic doses the drug causes little, if any, central nervous system (CNS) stimulation.


Dextromethorphan hydrobromide

Dextromethorphan hydrobromide acts centrally to elevate the threshold for coughing. It has no analgesic or addictive properties. The onset of antitussive action occurs in 15 to 30 minutes after administration and is of long duration.



How Supplied/Storage and Handling


16.1 How Supplied

Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid is an alcohol-free, sugar-free, dye-free, strawberry-flavored, clear liquid supplied in 16 oz. (473 mL) bottles, NDC 68032-456-16.


16.2 Storage and Handling

KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN. IN CASE OF ACCIDENTAL OVERDOSE, SEEK PROFESSIONAL ASSISTANCE OR CONTACT A POISON CONTROL CENTER IMMEDIATELY.

Store at 59°-86°F (15°-30°C) [See USP Controlled Room Temperature].

PHARMACIST: Dispense in a tight, light-resistant container as defined in the USP/NF with a child-resistant closure.



Patient Counseling Information


Patients receiving Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid should be given the following information:

1. Do not exceed the recommended dosage of Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid.

2. Report adverse experiences occurring during therapy.

3. Brom Mal/Phenyl HCl/ Dex HBr 4/7.5/15 mg/5 mL Liquid may cause drowsiness or excitability.


*Sections or subsections omitted from the full prescribing information are not listed.


Manufactured for:

River’s Edge Pharmaceuticals, LLC.

Suwanee, GA 30024

Rev. 01/10 456-10



PACKAGING


NDC 68032-456-16


Brom Mal/Phenyl HCl/Dex HBr 4/7.5/15mg/5 mL LIQUID


• ANTIHISTAMINE

• DECONGESTANT

• ANTITUSSIVE


Rx Only


Brompheniramine Maleate 4 mg/5 mL

Phenylephrine Hydrochloride 7.5 mg/5 mL

Dextromethorphan Hydrobromide 15 mg/5 mL


Strawberry Flavor


EACH TEASPOONFUL (5 mL) CONTAINS:

Brompheniramine Maleate ....... 4 mg

Phenylephrine HCl .................. 7.5 mg

Dextromethorphan HBr ........... 15 mg


16 fl oz (473 mL)












Brom Mal Phenyl HCl Dex HBr 
brompheniramine maleate, phenylephrine hydrochloride, dextromethorphan hydrobromide  liquid










Product Information
Product TypeHUMAN PRESCRIPTION DRUGNDC Product Code (Source)68032-456
Route of AdministrationORALDEA Schedule    














Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
BROMPHENIRAMINE MALEATE (BROMPHENIRAMINE)BROMPHENIRAMINE MALEATE4 mg  in 5 mL
PHENYLEPHRINE HYDROCHLORIDE (PHENYLEPHRINE)PHENYLEPHRINE HYDROCHLORIDE7.5 mg  in 5 mL
DEXTROMETHORPHAN HYDROBROMIDE (DEXTROMETHORPHAN)DEXTROMETHORPHAN HYDROBROMIDE15 mg  in 5 mL


















Inactive Ingredients
Ingredient NameStrength
GLYCERIN 
PROPYLENE GLYCOL 
SORBITOL 
CITRIC ACID MONOHYDRATE 
SODIUM CITRATE 
SACCHARIN SODIUM 
WATER 


















Product Characteristics
Color    Score    
ShapeSize
FlavorSTRAWBERRYImprint Code
Contains      










Packaging
#NDCPackage DescriptionMultilevel Packaging
168032-456-16473 mL In 1 BOTTLENone










Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
unapproved drug other02/10/2010


Labeler - River's Edge Pharmaceuticals, LLC (133879135)
Revised: 02/2010River's Edge Pharmaceuticals, LLC

More Brom Mal Phenyl HCl Dex HBr resources


  • Brom Mal Phenyl HCl Dex HBr Side Effects (in more detail)
  • Brom Mal Phenyl HCl Dex HBr Dosage
  • Brom Mal Phenyl HCl Dex HBr Use in Pregnancy & Breastfeeding
  • Brom Mal Phenyl HCl Dex HBr Drug Interactions
  • Brom Mal Phenyl HCl Dex HBr Support Group
  • 1 Review for Brom Mal Phenyl HCl Dex HBr - Add your own review/rating


Compare Brom Mal Phenyl HCl Dex HBr with other medications


  • Cough and Nasal Congestion

Somatuline Depot


Somatuline Depot is a brand name of lanreotide, approved by the FDA in the following formulation(s):


SOMATULINE DEPOT (lanreotide acetate - injectable; subcutaneous)



  • Manufacturer: IPSEN PHARMS

    Approval date: August 30, 2007

    Strength(s): EQ 120MG BASE [RLD], EQ 60MG BASE [RLD], EQ 90MG BASE [RLD]

Has a generic version of Somatuline Depot been approved?


No. There is currently no therapeutically equivalent version of Somatuline Depot available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Somatuline Depot. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Sustained release of peptides from pharmaceutical compositions
    Patent 5,595,760
    Issued: January 21, 1997
    Inventor(s): Cherif-Cheikh; Roland
    Assignee(s): Delab
    The invention features a method of administering a peptide to a patient and delivering the peptide continuously over an extended period of time of at least three days by obtaining a solid pharmaceutical composition including a soluble, gelable salt of the peptide and up to 30 percent, by weight, of a pharmaceutically acceptable, soluble, monomeric carrier, and parenterally administering the solid composition to the patient in one injection, wherein the solid composition automatically forms a gel after interaction with the patient's bodily fluids and releases the peptide continuously within the patient over an extended period of at least three days.
    Patent expiration dates:

    • March 8, 2020
      ✓ 
      Patent use: METHOD OF ADMINISTERING LANREOTIDE ACETATE
      ✓ 
      Drug product



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • August 30, 2012 - NEW CHEMICAL ENTITY

    • March 4, 2014 - EVERY 6 TO 8 WEEKS FOR THE 120MG STRENGTH FOR PATIENTS WHO ARE CONTROLLED ON SOMATULINE DEPOT 60MG OR 90MG

    • August 30, 2014 - ORPHAN DRUG EXCLUSIVITY

See also...

  • Somatuline Depot Consumer Information (Drugs.com)
  • Somatuline Depot Consumer Information (Wolters Kluwer)
  • Somatuline Depot Consumer Information (Cerner Multum)
  • Somatuline Depot Advanced Consumer Information (Micromedex)
  • Somatuline Depot AHFS DI Monographs (ASHP)
  • Lanreotide Consumer Information (Wolters Kluwer)
  • Lanreotide Consumer Information (Cerner Multum)
  • Lanreotide Subcutaneous Advanced Consumer Information (Micromedex)
  • Lanreotide Acetate AHFS DI Monographs (ASHP)

Friday, 18 November 2011

Myk 1




Myk 1 may be available in the countries listed below.


Ingredient matches for Myk 1



Sulconazole

Sulconazole nitrate (a derivative of Sulconazole) is reported as an ingredient of Myk 1 in the following countries:


  • Belgium

  • Luxembourg

International Drug Name Search

Thursday, 17 November 2011

Bioclindax




Bioclindax may be available in the countries listed below.


Ingredient matches for Bioclindax



Clindamycin

Clindamycin is reported as an ingredient of Bioclindax in the following countries:


  • Venezuela

International Drug Name Search

Epilexter




Epilexter may be available in the countries listed below.


Ingredient matches for Epilexter



Oxcarbazepine

Oxcarbazepine is reported as an ingredient of Epilexter in the following countries:


  • Spain

International Drug Name Search

Wednesday, 16 November 2011

Vicimex




Vicimex may be available in the countries listed below.


Ingredient matches for Vicimex



Ascorbic Acid

Ascorbic Acid is reported as an ingredient of Vicimex in the following countries:


  • Ethiopia

International Drug Name Search

Friday, 11 November 2011

Optivermin




Optivermin may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Optivermin



Fenbendazole

Fenbendazole is reported as an ingredient of Optivermin in the following countries:


  • Switzerland

Praziquantel

Praziquantel is reported as an ingredient of Optivermin in the following countries:


  • Switzerland

International Drug Name Search

Thursday, 10 November 2011

Bromhist-PDX Syrup


Pronunciation: brome-fen-EER-a-meen/dex-troe-meth-OR-fan/gwye-FEN-e-sin/fen-ill-EF-rin
Generic Name: Brompheniramine/Dextromethorphan/Guaifenesin/Phenylephrine
Brand Name: Examples include Accuhist PDX and Bromhist-PDX


Bromhist-PDX Syrup is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, cough, and throat and airway irritation due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.


Bromhist-PDX Syrup is an antihistamine, decongestant, cough suppressant, and expectorant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, loosening mucus and lung secretions in the chest, and making coughs more productive. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing while the cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.


Do NOT use Bromhist-PDX Syrup if:


  • you are allergic to any ingredient in Bromhist-PDX Syrup

  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems

  • you are unable to urinate or are having an asthma attack

  • you take sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Bromhist-PDX Syrup:


Some medical conditions may interact with Bromhist-PDX Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a fast, slow, or irregular heartbeat

  • if you have a history of adrenal gland problems (eg, adrenal gland tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your bladder, stomach, or intestines, ulcers, trouble urinating, an enlarged prostate or other prostate problems, seizures, or an overactive thyroid

  • if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if cough occurs with large amounts of mucus

Some MEDICINES MAY INTERACT with Bromhist-PDX Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Bromhist-PDX Syrup may be increased

  • Digoxin or droxidopa because risk of irregular heartbeat or heart attack may be increased

  • Bromocriptine or hydantoins (eg, phenytoin) because side effects may be increased by Bromhist-PDX Syrup

  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because effectiveness may be decreased by Bromhist-PDX Syrup

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bromhist-PDX Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Bromhist-PDX Syrup:


Use Bromhist-PDX Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Bromhist-PDX Syrup may be taken with or without food.

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you miss a dose of Bromhist-PDX Syrup, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bromhist-PDX Syrup.



Important safety information:


  • Bromhist-PDX Syrup may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Bromhist-PDX Syrup. Using Bromhist-PDX Syrup alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

  • Do not take diet or appetite control medicines while you are taking Bromhist-PDX Syrup without checking with your doctor.

  • Bromhist-PDX Syrup contains brompheniramine, dextromethorphan, and phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains brompheniramine, dextromethorphan, or phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.

  • Do NOT exceed the recommended dose or take Bromhist-PDX Syrup for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.

  • Bromhist-PDX Syrup may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Bromhist-PDX Syrup. Use a sunscreen or protective clothing if you must be outside for a prolonged period.

  • If you are scheduled for allergy skin testing, do not take Bromhist-PDX Syrup for several days before the test because it may decrease your response to the skin tests.

  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Bromhist-PDX Syrup.

  • Use Bromhist-PDX Syrup with caution in the ELDERLY because they may be more sensitive to its effects.

  • Caution is advised when using Bromhist-PDX Syrup in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Bromhist-PDX Syrup, discuss with your doctor the benefits and risks of using Bromhist-PDX Syrup during pregnancy. It is unknown if Bromhist-PDX Syrup is excreted in breast milk. Do not breast-feed while taking Bromhist-PDX Syrup.


Possible side effects of Bromhist-PDX Syrup:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Bromhist-PDX side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.


Proper storage of Bromhist-PDX Syrup:

Store Bromhist-PDX Syrup at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Bromhist-PDX Syrup out of the reach of children and away from pets.


General information:


  • If you have any questions about Bromhist-PDX Syrup, please talk with your doctor, pharmacist, or other health care provider.

  • Bromhist-PDX Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bromhist-PDX Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bromhist-PDX resources


  • Bromhist-PDX Side Effects (in more detail)
  • Bromhist-PDX Use in Pregnancy & Breastfeeding
  • Bromhist-PDX Drug Interactions
  • Bromhist-PDX Support Group
  • 0 Reviews for Bromhist-PDX - Add your own review/rating


Compare Bromhist-PDX with other medications


  • Cough and Nasal Congestion

Saturday, 5 November 2011

Toprol-XL


Toprol-XL is a brand name of metoprolol, approved by the FDA in the following formulation(s):


TOPROL-XL (metoprolol succinate - tablet, extended release; oral)



  • Manufacturer: ASTRAZENECA

    Approval date: January 10, 1992

    Strength(s): EQ 100MG TARTRATE [AB], EQ 200MG TARTRATE [RLD][AB], EQ 50MG TARTRATE [RLD][AB]


  • Manufacturer: ASTRAZENECA

    Approval date: February 5, 2001

    Strength(s): EQ 25MG TARTRATE [AB]

Has a generic version of Toprol-XL been approved?


A generic version of Toprol-XL has been approved by the FDA. However, this does not mean that the product will necessarily be commercially available - possibly because of drug patents and/or drug exclusivity. The following products are equivalent to Toprol-XL and have been approved by the FDA:


metoprolol succinate tablet, extended release; oral



  • Manufacturer: MYLAN PHARMS INC

    Approval date: December 15, 2011

    Strength(s): EQ 100MG TARTRATE [AB], EQ 200MG TARTRATE [AB], EQ 25MG TARTRATE [AB], EQ 50MG TARTRATE [AB]


  • Manufacturer: NESHER PHARMS

    Approval date: May 18, 2007

    Strength(s): EQ 100MG TARTRATE [AB], EQ 200MG TARTRATE [AB]


  • Manufacturer: NESHER PHARMS

    Approval date: March 20, 2008

    Strength(s): EQ 25MG TARTRATE [AB]


  • Manufacturer: NESHER PHARMS

    Approval date: May 14, 2008

    Strength(s): EQ 50MG TARTRATE [AB]


  • Manufacturer: SANDOZ

    Approval date: July 31, 2006

    Strength(s): EQ 25MG TARTRATE [AB]


  • Manufacturer: SANDOZ

    Approval date: May 18, 2007

    Strength(s): EQ 50MG TARTRATE [AB]


  • Manufacturer: SANDOZ

    Approval date: March 20, 2008

    Strength(s): EQ 100MG TARTRATE [AB], EQ 200MG TARTRATE [AB]


  • Manufacturer: WATSON LABS FLORIDA

    Approval date: August 3, 2009

    Strength(s): EQ 25MG TARTRATE [AB], EQ 50MG TARTRATE [AB]


  • Manufacturer: WATSON LABS FLORIDA

    Approval date: April 15, 2010

    Strength(s): EQ 100MG TARTRATE [AB], EQ 200MG TARTRATE [AB]


  • Manufacturer: WOCKHARDT

    Approval date: July 22, 2010

    Strength(s): EQ 100MG TARTRATE [AB], EQ 200MG TARTRATE [AB], EQ 25MG TARTRATE [AB], EQ 50MG TARTRATE [AB]

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Toprol-XL. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents

There are no current U.S. patents associated with Toprol-XL.

Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • July 18, 2010 - REVISIONS TO LABELING BASED ON DATA SUBMITTED IN RESPONSE TO PEDIATRIC WRITTEN REQUEST

    • January 18, 2011 - PEDIATRIC EXCLUSIVITY

See also...

  • Toprol Consumer Information (Drugs.com)
  • Toprol XL Extended-Release Tablets Consumer Information (Wolters Kluwer)
  • Toprol-XL Consumer Information (Cerner Multum)
  • Toprol XL Advanced Consumer Information (Micromedex)
  • Metoprolol Consumer Information (Drugs.com)
  • Metoprolol Succinate Extended-Release Tablets Consumer Information (Wolters Kluwer)
  • Metoprolol Tartrate Consumer Information (Wolters Kluwer)
  • Metoprolol Tartrate Tablets Consumer Information (Wolters Kluwer)
  • Metoprolol Tartrate Consumer Information (Cerner Multum)
  • Metoprolol Consumer Information (Cerner Multum)
  • Metoprolol Advanced Consumer Information (Micromedex)
  • Metoprolol Intravenous Advanced Consumer Information (Micromedex)
  • Metoprolol Succinate AHFS DI Monographs (ASHP)
  • Metoprolol Tartrate AHFS DI Monographs (ASHP)

Friday, 4 November 2011

diclofenac transdermal



Generic Name: diclofenac transdermal (dye KLOE fen ak)

Brand Names: Flector Patch


What is diclofenac transdermal?

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.


Diclofenac transdermal skin patch is used to treat pain caused by minor sprains, strains, or bruising.


Diclofenac transdermal may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about diclofenac transdermal?


Do not use this medication if you have ever had asthma or a severe allergic reaction caused by aspirin, diclofenac (Cataflam, Voltaren), or another non-steroidal anti-inflammatory drug (NSAID). Do not use diclofenac just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have heart disease, congestive heart failure, high blood pressure, a history of heart attack or stroke, a history of stomach ulcer or bleeding, liver or kidney disease, a blood clotting disorder, asthma or polyps in your nose, or if you smoke.


While the risk of absorbing diclofenac transdermal into your bloodstream is low, an NSAID may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.


Get emergency medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are using diclofenac transdermal, especially in older adults.


Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

What should I discuss with my healthcare provider before using diclofenac transdermal?


While the risk of absorbing diclofenac transdermal into your bloodstream is low, an NSAID can cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.


This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are using diclofenac transdermal, especially in older adults.


Do not use this medication if you have ever had asthma or a severe allergic reaction caused by aspirin, diclofenac (Cataflam, Voltaren), or another NSAID. Do not use diclofenac just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medicine:



  • a history of drug allergies;




  • a history of heart attack, stroke, or blood clot;




  • heart disease, congestive heart failure, high blood pressure;




  • a history of stomach ulcer or bleeding;



  • liver or kidney disease;


  • a bleeding or blood clotting disorder;




  • asthma;




  • polyps in your nose; or




  • if you smoke.




FDA pregnancy category C. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Using diclofenac during the last 3 months of pregnancy may harm the unborn baby. Do not use this medication during pregnancy unless your doctor has told you to. It is not known whether diclofenac transdermal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use diclofenac transdermal?


Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Using extra skin patches will not make the medication more effective. Follow the directions on your prescription label.


Apply the skin patch directly to the area of pain. The skin patch can be worn for up to 12 hours and then removed. Apply a new patch at that time if pain continues. Do not wear a skin patch while taking a bath or shower or while swimming.


Do not apply diclofenac transdermal on an open skin wound, or on areas of eczema, infection, skin rash, or burn injury. Wash your hands after applying or removing a skin patch.

If the patch falls off, try sticking it back on, or use medical tape to hold it on.


After removing a skin patch fold it in half, sticky side in, and throw it away in a place where children or pets cannot get to it. Keep both used and unused skin patches out of the reach of children or pets.

If you use this medication long-term, your blood may need to be tested often. Your blood pressure may also need to be checked. Visit your doctor regularly.


The diclofenac transdermal patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test. Store at room temperature away from moisture and heat. Do not take a skin patch out of the patch envelope until you are ready to use it. Reseal the envelope for storage.

What happens if I miss a dose?


Apply a skin patch as soon as you remember, and wear it for 12 hours before applying a new one. Do not use extra patches to make up the missed dose. Do not wear a diclofenac skin patch for longer than 12 hours.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using diclofenac transdermal?


Avoid drinking alcohol. It may increase your risk of stomach bleeding.

Avoid taking aspirin, oral (pill form) diclofenac (Cataflam, Voltaren), or other NSAIDs without your doctor's advice. This includes ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others.


Ask a doctor or pharmacist before using any over-the-counter cold, allergy, or pain medicine. Many combination medicines contain aspirin or other medicines similar to diclofenac (such as ibuprofen, ketoprofen, or naproxen). Taking certain products together can cause you to get too much of this type of medication. Check the label to see if a medicine contains aspirin, ibuprofen, ketoprofen, or naproxen. Avoid getting this medication near your eyes. If this does happen, rinse with water and call your doctor if you have eye irritation that lasts longer than 1 hour.

Diclofenac transdermal side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when diclofenac is applied to the skin, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.


Stop using this medicine and call your doctor at once if you have a serious side effect such as:

  • chest pain, slurred speech, problems with vision or balance, and feeling weak or short of breath;




  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;




  • fever, chills, body aches, flu symptoms;




  • pale or yellowed skin, dark colored urine, confusion;




  • swelling or rapid weight gain;




  • urinating less than usual or not at all;




  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);




  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness;




  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or




  • the first sign of any skin rash, no matter how mild.



Less serious side effects may include:



  • mild nausea, vomiting;




  • diarrhea, constipation;




  • upset stomach, heartburn, gas;




  • dizziness; or




  • mild itching, burning, redness, or other skin irritation where the patch was worn.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Diclofenac transdermal Dosing Information


Usual Adult Dose for Keratosis:

3% Gel: Apply amount sufficient to cover each actinic keratosis lesion twice daily and rub in gently for 60 to 90 days. Complete healing of lesions may not be evident for 30 days after discontinuation of therapy.

Usual Adult Dose for Osteoarthritis:

1% Gel:
Apply the gel (4 g) to the affected foot or knee or ankle four times daily and rub in gently. Do not apply more than 16 g daily to any single joint of the lower extremities.

Apply the gel (2 g) to the affected hand or elbow or wrist four times daily and rub in gently. Do not apply more than 8 g daily to any single joint of the upper extremities.

Total dose should not exceed 32 g per day, over all affected joints.

Topical solution 1.5%:
10 drops at a time either directly onto the knee or first into the hand and then onto the knee. Spread around evenly around front, back, and sides of the knee. Repeat this procedure until 40 drops have been applied and the knee is completely covered with solution. Wash hands completely after administering product. Wait until the area is completely dry before covering with clothing or applying sunscreen, insect repellent, cosmetics, topical medications, or other substances.

Usual Adult Dose for Pain:

1.3% topical patch:
Acute pain due to minor strains, sprains, and contusions:
Apply one patch to the most painful area twice a day.


What other drugs will affect diclofenac transdermal?


Tell your doctor about all other medicines you use, especially:



  • a blood thinner such as warfarin (Coumadin);




  • cyclosporine (Gengraf, Neoral, Sandimmune);




  • lithium (Eskalith, Lithobid);




  • methotrexate (Rheumatrex, Trexall);




  • a diuretic (water pill);




  • steroids (prednisone and others); or




  • heart or blood pressure medication such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others.



It is not likely that other drugs you take orally or inject will have an effect on topically applied diclofenac. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More diclofenac transdermal resources


  • Diclofenac transdermal Dosage
  • Diclofenac transdermal Use in Pregnancy & Breastfeeding
  • Diclofenac transdermal Drug Interactions
  • Diclofenac transdermal Support Group
  • 83 Reviews for Diclofenac - Add your own review/rating


Compare diclofenac transdermal with other medications


  • Actinic Keratosis
  • Osteoarthritis
  • Pain


Where can I get more information?


  • Your pharmacist can provide more information about diclofenac transdermal.


Friday, 28 October 2011

Bodix




Bodix may be available in the countries listed below.


Ingredient matches for Bodix



Budesonide

Budesonide is reported as an ingredient of Bodix in the following countries:


  • Italy

International Drug Name Search

Thursday, 27 October 2011

Deca-Vinone




Deca-Vinone may be available in the countries listed below.


Ingredient matches for Deca-Vinone



Nandrolone

Nandrolone 17ß-decanoate (a derivative of Nandrolone) is reported as an ingredient of Deca-Vinone in the following countries:


  • Bahrain

  • Egypt

  • Iraq

  • Jordan

  • Kuwait

  • Lebanon

  • Libya

  • Qatar

  • Saudi Arabia

  • Sudan

  • Syria

  • United Arab Emirates

  • Yemen

International Drug Name Search

Wednesday, 26 October 2011

Dilcoran




Dilcoran may be available in the countries listed below.


Ingredient matches for Dilcoran



Pentaerithrityl Tetranitrate

Pentaerithrityl Tetranitrate is reported as an ingredient of Dilcoran in the following countries:


  • Serbia

International Drug Name Search

Saturday, 22 October 2011

Oksaliplatin Medac




Oksaliplatin Medac may be available in the countries listed below.


Ingredient matches for Oksaliplatin Medac



Oxaliplatin

Oxaliplatin is reported as an ingredient of Oksaliplatin Medac in the following countries:


  • Estonia

  • Lithuania

International Drug Name Search

Wednesday, 5 October 2011

Biocanisspray




Biocanisspray may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Biocanisspray



Chlorhexidine

Chlorhexidine digluconate (a derivative of Chlorhexidine) is reported as an ingredient of Biocanisspray in the following countries:


  • France

International Drug Name Search

Tuesday, 4 October 2011

Esaldox




Esaldox may be available in the countries listed below.


Ingredient matches for Esaldox



Levothyroxine

Levothyroxine sodium salt (a derivative of Levothyroxine) is reported as an ingredient of Esaldox in the following countries:


  • Chile

International Drug Name Search

Tuesday, 27 September 2011

Elspar




In the US, Elspar (asparaginase systemic) is a member of the drug class miscellaneous antineoplastics and is used to treat Acute Lymphocytic Leukemia.

US matches:

  • Elspar

Ingredient matches for Elspar



Asparaginase

Asparaginase is reported as an ingredient of Elspar in the following countries:


  • United States

International Drug Name Search

Friday, 23 September 2011

Olapine




Olapine may be available in the countries listed below.


Ingredient matches for Olapine



Olanzapine

Olanzapine is reported as an ingredient of Olapine in the following countries:


  • Greece

International Drug Name Search

Thursday, 22 September 2011

Norapred




Norapred may be available in the countries listed below.


Ingredient matches for Norapred



Prednisone

Prednisone is reported as an ingredient of Norapred in the following countries:


  • Mexico

International Drug Name Search

Wednesday, 21 September 2011

Histaxin




Histaxin may be available in the countries listed below.


Ingredient matches for Histaxin



Diphenhydramine

Diphenhydramine hydrochloride (a derivative of Diphenhydramine) is reported as an ingredient of Histaxin in the following countries:


  • Austria

International Drug Name Search

Sunday, 18 September 2011

Fluorouacil Teva




Fluorouacil Teva may be available in the countries listed below.


Ingredient matches for Fluorouacil Teva



Fluorouracil

Fluorouracil is reported as an ingredient of Fluorouacil Teva in the following countries:


  • Latvia

  • Netherlands

International Drug Name Search

Thursday, 15 September 2011

Ranitidin Mylan




Ranitidin Mylan may be available in the countries listed below.


Ingredient matches for Ranitidin Mylan



Ranitidine

Ranitidine hydrochloride (a derivative of Ranitidine) is reported as an ingredient of Ranitidin Mylan in the following countries:


  • Sweden

International Drug Name Search

Wednesday, 14 September 2011

Estriol Succinate




Estriol Succinate may be available in the countries listed below.


Ingredient matches for Estriol Succinate



Estriol

Estriol Succinate (BAN) is known as Estriol in the US.

International Drug Name Search

Glossary

BANBritish Approved Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Tuesday, 13 September 2011

Oxymetazoline Solution


Pronunciation: OX-ee-MET-azz-oh-leen
Generic Name: Oxymetazoline
Brand Name: Examples include Afrin and Nostrilla 12 Hour


Oxymetazoline Solution is used for:

Relieving nasal congestion due to the common cold, hay fever, other upper respiratory tract allergies, or sinus infection. It may also be used to treat other conditions as determined by your doctor.


Oxymetazoline Solution is a decongestant. It works by shrinking swollen and congested nasal tissues (mucous membranes) by constricting blood vessels. This results in relief of congestion (stuffy feeling), improved drainage of mucus, and improved breathing through the nose. Local application (eg, nose drops and sprays) causes more intense and rapid vasoconstriction than oral medicines (eg, tablets, syrups).


Do NOT use Oxymetazoline Solution if:


  • you are allergic to any ingredient in Oxymetazoline Solution

  • you are also taking furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Oxymetazoline Solution:


Some medical conditions may interact with Oxymetazoline Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have high blood pressure, enlarged prostate, diabetes, overactive thyroid, or heart disease

Some MEDICINES MAY INTERACT with Oxymetazoline Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Tricyclic antidepressants (eg, amitriptyline) because the effectiveness of Oxymetazoline Solution may be decreased

  • Cocaine, furazolidone, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because side effects, such as headache, fever, or high blood pressure, may be increased

  • Bromocriptine or cocaine because the actions and side effects of these medicines may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Oxymetazoline Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Oxymetazoline Solution:


Use Oxymetazoline Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • To use nose drops, gently blow your nose. Lie down and tilt your head back. Breathe through your mouth. Insert the dropper tip in the nose no more than 1/3 inch. Try not to touch the dropper tip to the inside of your nose. Place the correct number of drops in your nose. Continue to lie down with your head tilted back for 2 minutes.

  • To use a nose spray, gently blow your nose. Sit down and tilt your head back slightly. Place the tip of the spray container into the nose. Using a finger from your other hand, press against the opposite nostril to close it off. Breathe gently through the open nostril and squeeze the spray container. If you are using more than 1 spray, wait for 1 to 2 minutes between sprays. After using the medicine, rinse the tip of the spray unit in hot water and dry with a clean tissue to prevent contamination.

  • If you miss a dose of Oxymetazoline Solution and are using it regularly, use it as soon as possible. If it is much more than 1 hour since your missed dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Oxymetazoline Solution.



Important safety information:


  • Do not use Oxymetazoline Solution for more than 3 days unless advised to do so by your health care provider. Frequent or long-term use of Oxymetazoline Solution may cause nasal congestion to recur or worsen.

  • Do not share Oxymetazoline Solution with anyone else; this may cause the infection to spread.

  • Diabetes patients - Oxymetazoline Solution may affect your blood sugar level. Your doctor may need to change the amount of diabetes medicine you are taking.

  • Oxymetazoline Solution is not recommended for use in CHILDREN younger than 6 years of age. Safety and effectiveness in this age group have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Oxymetazoline Solution during pregnancy. It is unknown if Oxymetazoline Solution is excreted in breast milk. If you are or will be breast-feeding while you are using Oxymetazoline Solution, check with your doctor or pharmacist to discuss the risks to your baby.


Possible side effects of Oxymetazoline Solution:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Increase in nasal discharge; sneezing; stinging; temporary burning.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Oxymetazoline Solution:

Store Oxymetazoline Solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) in a tightly-closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Oxymetazoline Solution out of the reach of children and away from pets.


General information:


  • If you have any questions about Oxymetazoline Solution, please talk with your doctor, pharmacist, or other health care provider.

  • Oxymetazoline Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Oxymetazoline Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Oxymetazoline resources


  • Oxymetazoline Use in Pregnancy & Breastfeeding
  • Oxymetazoline Drug Interactions
  • Oxymetazoline Support Group
  • 12 Reviews for Oxymetazoline - Add your own review/rating


Compare Oxymetazoline with other medications


  • Nasal Congestion

Monday, 12 September 2011

Albadry Plus




In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Albadry Plus



Benzylpenicillin

Benzylpenicillin procaine (a derivative of Benzylpenicillin) is reported as an ingredient of Albadry Plus in the following countries:


  • United States

Novobiocin

Novobiocin sodium salt (a derivative of Novobiocin) is reported as an ingredient of Albadry Plus in the following countries:


  • United States

International Drug Name Search

Sunday, 11 September 2011

Timoptic




In the US, Timoptic (timolol ophthalmic) is a member of the drug class ophthalmic glaucoma agents and is used to treat Glaucoma - Open Angle and Intraocular Hypertension.

US matches:

  • Timoptic Drops

  • Timoptic XE Gel Eye Drops

  • Timoptic Ocudose

  • Timoptic Ocumeter

  • Timoptic Ocumeter Plus

  • Timoptic-XE

  • Timoptic-XE Ocumeter

  • Timoptic-XE Ocumeter Plus

  • Timoptic

  • Timoptic XE

  • Timoptic in Ocudose

Ingredient matches for Timoptic



Timolol

Timolol maleate (a derivative of Timolol) is reported as an ingredient of Timoptic in the following countries:


  • Austria

  • Canada

  • Estonia

  • Peru

  • Poland

  • Romania

  • Switzerland

  • United States

International Drug Name Search

Friday, 9 September 2011

Emarfen




Emarfen may be available in the countries listed below.


Ingredient matches for Emarfen



Alfacalcidol

Alfacalcidol is reported as an ingredient of Emarfen in the following countries:


  • Greece

International Drug Name Search

Hysan-Baby




Hysan-Baby may be available in the countries listed below.


Ingredient matches for Hysan-Baby



Hyaluronic Acid

Hyaluronic Acid sodium salt (a derivative of Hyaluronic Acid) is reported as an ingredient of Hysan-Baby in the following countries:


  • Germany

International Drug Name Search

Thursday, 8 September 2011

Pacium




Pacium may be available in the countries listed below.


Ingredient matches for Pacium



Diazepam

Diazepam is reported as an ingredient of Pacium in the following countries:


  • Spain

Pyridoxine

Pyridoxine hydrochloride (a derivative of Pyridoxine) is reported as an ingredient of Pacium in the following countries:


  • Spain

International Drug Name Search

Isoaminile




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

R05DB04

CAS registry number (Chemical Abstracts Service)

0000077-51-0

Chemical Formula

C16-H24-N2

Molecular Weight

244

Therapeutic Category

Cough suppressant

Chemical Name

Benzeneacetonitrile, α-[2-(dimethylamino)propyl]-α-(1-methylethyl)-

Foreign Names

  • Isoaminilum (Latin)
  • Isoaminil (German)
  • Isoaminile (French)
  • Isoaminilo (Spanish)

Generic Names

  • Isoaminile (OS: BAN, DCF, DCIT)
  • W 7 (IS)
  • Isoaminile (PH: BP 2002)

Brand Name

  • Peracon
    Solvay, Indonesia

International Drug Name Search

Glossary

BANBritish Approved Name
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Tuesday, 6 September 2011

Tetrasina




Tetrasina may be available in the countries listed below.


Ingredient matches for Tetrasina



Tetracycline

Tetracycline hydrochloride (a derivative of Tetracycline) is reported as an ingredient of Tetrasina in the following countries:


  • Bangladesh

International Drug Name Search

Iodine in Alcohol




Iodine in Alcohol may be available in the countries listed below.


Ingredient matches for Iodine in Alcohol



Povidone Iodine

Povidone-Iodine is reported as an ingredient of Iodine in Alcohol in the following countries:


  • New Zealand

International Drug Name Search

Monday, 5 September 2011

Eszo




Eszo may be available in the countries listed below.


Ingredient matches for Eszo



Estazolam

Estazolam is reported as an ingredient of Eszo in the following countries:


  • Taiwan

Eszopiclone

Eszopiclone is reported as an ingredient of Eszo in the following countries:


  • Bangladesh

International Drug Name Search

Thursday, 1 September 2011

Ropinirol Mylan




Ropinirol Mylan may be available in the countries listed below.


Ingredient matches for Ropinirol Mylan



Ropinirole

Ropinirole hydrochloride (a derivative of Ropinirole) is reported as an ingredient of Ropinirol Mylan in the following countries:


  • Slovakia

  • Sweden

International Drug Name Search

Friday, 26 August 2011

Fluorouracile Winthrop




Fluorouracile Winthrop may be available in the countries listed below.


Ingredient matches for Fluorouracile Winthrop



Fluorouracil

Fluorouracil is reported as an ingredient of Fluorouracile Winthrop in the following countries:


  • France

International Drug Name Search

Friday, 19 August 2011

Metoprolol PC




Metoprolol PC may be available in the countries listed below.


Ingredient matches for Metoprolol PC



Metoprolol

Metoprolol succinate (a derivative of Metoprolol) is reported as an ingredient of Metoprolol PC in the following countries:


  • Netherlands

International Drug Name Search

Aspirin Cardio




Aspirin Cardio may be available in the countries listed below.


Ingredient matches for Aspirin Cardio



Aspirin

Acetylsalicylic Acid is reported as an ingredient of Aspirin Cardio in the following countries:


  • Georgia

  • Russian Federation

  • Singapore

  • Switzerland

International Drug Name Search

Thursday, 18 August 2011

Isoriac




Isoriac may be available in the countries listed below.


Ingredient matches for Isoriac



Isotretinoin

Isotretinoin is reported as an ingredient of Isoriac in the following countries:


  • Italy

International Drug Name Search

Wednesday, 17 August 2011

Cefoperazona Fabra




Cefoperazona Fabra may be available in the countries listed below.


Ingredient matches for Cefoperazona Fabra



Cefoperazone

Cefoperazone sodium salt (a derivative of Cefoperazone) is reported as an ingredient of Cefoperazona Fabra in the following countries:


  • Argentina

International Drug Name Search

Monday, 15 August 2011

Elcatonina




Elcatonina may be available in the countries listed below.


Ingredient matches for Elcatonina



Elcatonin

Elcatonina (DCIT) is also known as Elcatonin (Rec.INN)

International Drug Name Search

Glossary

DCITDenominazione Comune Italiana
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Saturday, 13 August 2011

Nalmefene




In the US, Nalmefene (nalmefene systemic) is a member of the drug class antidotes and is used to treat Opioid Overdose and Reversal of Opioid Sedation.

US matches:

  • Nalmefene

  • Nalmefene Hydrochloride

Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

0055096-26-9

Chemical Formula

C21-H25-N-O3

Molecular Weight

339

Therapeutic Category

Opioid receptor antagonist

Chemical Name

Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, (5α)-

Foreign Names

  • Nalmefenum (Latin)
  • Nalmefen (German)
  • Nalmefene (French)
  • Nalmefeno (Spanish)

Generic Names

  • Nalmefene (OS: BAN, USAN)
  • JF 1 (IS: Key)
  • Nalmetrene (IS)
  • ORF 11676 (IS)
  • Nalmefene Hydrochloride (OS: BANM)

Brand Name

  • Revex
    Baxter, United States

International Drug Name Search

Glossary

BANBritish Approved Name
BANMBritish Approved Name (Modified)
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.