Friday, 24 December 2010

Berinert




In the US, Berinert (C1 esterase inhibitor (human) systemic) is a member of the drug class miscellaneous coagulation modifiers and is used to treat Hereditary Angioedema.

US matches:

  • Berinert

UK matches:

  • Berinert (SPC)

Ingredient matches for Berinert



C1 Esterase Inhibitor, human

C1 Esterase Inhibitor, human is reported as an ingredient of Berinert in the following countries:


  • Argentina

  • Austria

  • Germany

  • Greece

  • Hungary

  • Slovakia

  • Spain

  • Sweden

  • Switzerland

  • United Kingdom

  • United States

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Saturday, 11 December 2010

Bonasanit




Bonasanit may be available in the countries listed below.


Ingredient matches for Bonasanit



Pyridoxine

Pyridoxine hydrochloride (a derivative of Pyridoxine) is reported as an ingredient of Bonasanit in the following countries:


  • Germany

International Drug Name Search

Friday, 10 December 2010

Drotrecogin Alfa (activated)




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

B01AD10

CAS registry number (Chemical Abstracts Service)

0098530-76-8

Chemical Formula

C2071-H3165-N581-O640-S31

Molecular Weight

47438

Therapeutic Category

Anticoagulant: Thrombin inhibitor

Chemical Name

Blood-coagulation factor XIV (human) (WHO)

Foreign Names

  • Drotrecoginum alfa (activatum) (Latin)
  • Drotrecogin alfa (aktiviert) (German)
  • Drotrécogine alfa (activé) (French)
  • Drotrecogina alfa (activada) (Spanish)

Generic Names

  • Drotrecogin Alfa (activated) (OS: BAN, USAN)
  • Human activated protein C, recombinant (IS)
  • LY 203638 (IS: Eli Lilly)
  • Protein C human, recombinant (IS)
  • Recombinant human activated protein C (IS)
  • Rekombinantes humanes aktiviertes Protein C (rhAPC). (IS)
  • rhAPC (IS)

Brand Names

  • Xigris
    Eli Lilly, Canada; Eli Lilly, United Kingdom; Eli Lilly, Netherlands; Eli Lilly, Oman; Eli Lilly, South Africa; Eli Lilly NL B.V., Luxembourg; Lilly, Argentina; Lilly, Austria; Lilly, Australia; Lilly, Belgium; Lilly, Switzerland; Lilly, Chile; Lilly, Czech Republic; Lilly, Germany; Lilly, Denmark; Lilly, Spain; Lilly, Finland; Lilly, France; Lilly, Hong Kong; Lilly, Croatia (Hrvatska); Lilly, Hungary; Lilly, Ireland; Lilly, Israel; Lilly, India; Lilly, Iceland; Lilly, Italy; Lilly, Mexico; Lilly, Malaysia; Lilly, Norway; Lilly, New Zealand; Lilly, Poland; Lilly, Romania; Lilly, Russian Federation; Lilly, Sweden; Lilly, Singapore; Lilly, Slovenia; Lilly, Slovakia; Lilly, Turkey; Lilly, Taiwan; Lilly, United States

International Drug Name Search

Glossary

BANBritish Approved Name
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Thursday, 18 November 2010

Aphilan démangeaisons




Aphilan démangeaisons may be available in the countries listed below.


Ingredient matches for Aphilan démangeaisons



Hydrocortisone

Hydrocortisone 21-acetate (a derivative of Hydrocortisone) is reported as an ingredient of Aphilan démangeaisons in the following countries:


  • France

International Drug Name Search

Monday, 15 November 2010

Abitren Inject




Abitren Inject may be available in the countries listed below.


Ingredient matches for Abitren Inject



Diclofenac

Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Abitren Inject in the following countries:


  • Israel

International Drug Name Search

Quinimax




Quinimax may be available in the countries listed below.


Ingredient matches for Quinimax



Quinine

Quinine hydrochloride (a derivative of Quinine) is reported as an ingredient of Quinimax in the following countries:


  • France

  • Ghana

  • Kenya

  • Nigeria

  • Tanzania

  • Uganda

International Drug Name Search

Monday, 8 November 2010

Dacarbazina Filaxis




Dacarbazina Filaxis may be available in the countries listed below.


Ingredient matches for Dacarbazina Filaxis



Dacarbazine

Dacarbazine is reported as an ingredient of Dacarbazina Filaxis in the following countries:


  • Argentina

  • Peru

International Drug Name Search

Rovamycine




Rovamycine may be available in the countries listed below.


Ingredient matches for Rovamycine



Spiramycin

Spiramycin is reported as an ingredient of Rovamycine in the following countries:


  • Bangladesh

  • Belgium

  • Benin

  • Bulgaria

  • Burkina Faso

  • Cameroon

  • Canada

  • Central African Republic

  • Chad

  • Congo

  • Cote D'ivoire

  • Czech Republic

  • Estonia

  • France

  • Gabon

  • Georgia

  • Germany

  • Ghana

  • Guinea

  • Hong Kong

  • Hungary

  • Indonesia

  • Israel

  • Kenya

  • Latvia

  • Luxembourg

  • Madagascar

  • Malaysia

  • Mali

  • Mauritania

  • Mauritius

  • Niger

  • Nigeria

  • Poland

  • Portugal

  • Romania

  • Russian Federation

  • Senegal

  • Singapore

  • Spain

  • Switzerland

  • Togo

  • Tunisia

  • Turkey

  • Vietnam

  • Zaire

  • Zimbabwe

Spiramycin adipate (a derivative of Spiramycin) is reported as an ingredient of Rovamycine in the following countries:


  • Czech Republic

  • France

International Drug Name Search

Wednesday, 27 October 2010

Cloriflox




Cloriflox may be available in the countries listed below.


Ingredient matches for Cloriflox



Fluoxetine

Fluoxetine hydrochloride (a derivative of Fluoxetine) is reported as an ingredient of Cloriflox in the following countries:


  • Italy

International Drug Name Search

Tuesday, 26 October 2010

Klasol




Klasol may be available in the countries listed below.


Ingredient matches for Klasol



Clarithromycin

Clarithromycin is reported as an ingredient of Klasol in the following countries:


  • Turkey

International Drug Name Search

Carvedilol KRKA




Carvedilol KRKA may be available in the countries listed below.


Ingredient matches for Carvedilol KRKA



Carvedilol

Carvedilol is reported as an ingredient of Carvedilol KRKA in the following countries:


  • Denmark

International Drug Name Search

Monday, 25 October 2010

Apo-Valproic




Apo-Valproic may be available in the countries listed below.


Ingredient matches for Apo-Valproic



Valproic Acid

Valproic Acid is reported as an ingredient of Apo-Valproic in the following countries:


  • Canada

  • Guyana

International Drug Name Search

Sunday, 24 October 2010

Rifamycin Sodium




Rifamycin Sodium may be available in the countries listed below.


Ingredient matches for Rifamycin Sodium



Rifamycin

Rifamycin Sodium (BANM) is also known as Rifamycin (Rec.INN)

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Friday, 22 October 2010

Eprosartan Hydrochlorothiazide Tora




Eprosartan Hydrochlorothiazide Tora may be available in the countries listed below.


Ingredient matches for Eprosartan Hydrochlorothiazide Tora



Eprosartan

Eprosartan mesilate (a derivative of Eprosartan) is reported as an ingredient of Eprosartan Hydrochlorothiazide Tora in the following countries:


  • Spain

Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Eprosartan Hydrochlorothiazide Tora in the following countries:


  • Spain

International Drug Name Search

Tuesday, 19 October 2010

Heparina Sodica Trifarma




Heparina Sodica Trifarma may be available in the countries listed below.


Ingredient matches for Heparina Sodica Trifarma



Heparin

Heparin sodium salt (a derivative of Heparin) is reported as an ingredient of Heparina Sodica Trifarma in the following countries:


  • Peru

International Drug Name Search

Oxipelle




Oxipelle may be available in the countries listed below.


Ingredient matches for Oxipelle



Oxiconazole

Oxiconazole nitrate (a derivative of Oxiconazole) is reported as an ingredient of Oxipelle in the following countries:


  • Brazil

International Drug Name Search

Bisoprolol plus-1A Pharma




Bisoprolol plus-1A Pharma may be available in the countries listed below.


Ingredient matches for Bisoprolol plus-1A Pharma



Bisoprolol

Bisoprolol fumarate (a derivative of Bisoprolol) is reported as an ingredient of Bisoprolol plus-1A Pharma in the following countries:


  • Germany

Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Bisoprolol plus-1A Pharma in the following countries:


  • Germany

International Drug Name Search

Saturday, 16 October 2010

Ceftaridem




Ceftaridem may be available in the countries listed below.


Ingredient matches for Ceftaridem



Ceftazidime

Ceftazidime pentahydrate (a derivative of Ceftazidime) is reported as an ingredient of Ceftaridem in the following countries:


  • Greece

International Drug Name Search

Friday, 15 October 2010

Advil enfant et nourrisson




Advil enfant et nourrisson may be available in the countries listed below.


Ingredient matches for Advil enfant et nourrisson



Ibuprofen

Ibuprofen is reported as an ingredient of Advil enfant et nourrisson in the following countries:


  • France

International Drug Name Search

Thursday, 14 October 2010

Amisulprid Lich




Amisulprid Lich may be available in the countries listed below.


Ingredient matches for Amisulprid Lich



Amisulpride

Amisulpride is reported as an ingredient of Amisulprid Lich in the following countries:


  • Germany

International Drug Name Search

Wednesday, 13 October 2010

Differin





Dosage Form: gel
FULL PRESCRIBING INFORMATION

Indications and Usage for Differin


Differin Gel, 0.3% is indicated for the topical treatment of acne vulgaris in patients 12 years of age and older.



Differin Dosage and Administration


Apply a thin film of Differin Gel, 0.3% to the entire face and any other affected areas of the skin once daily in the evening, after washing gently with a non-medicated soap.  Avoid application to the areas of skin around eyes, lips, and mucous membranes.  A mild transitory sensation of warmth or slight stinging may occur shortly after the application of Differin Gel, 0.3%.  Patients should be instructed to minimize sun exposure.  Patients may be instructed to use moisturizers for relief of dry skin or irritation.


If therapeutic results are not noticed after 12 weeks of treatment, therapy should be re-evaluated.


For topical use only.  Not for ophthalmic, oral or intravaginal use.



Dosage Forms and Strengths


Each gram of Differin Gel, 0.3% contains 3 mg adapalene in an off-white aqueous gel.



Contraindications


Differin Gel, 0.3% should not be administered to individuals who are hypersensitive to adapalene or any of the components in the gel vehicle.



Warnings and Precautions



Ultraviolet Light and Environmental Exposure


Exposure to sunlight, including sunlamps, should be minimized during use of Differin Gel, 0.3%.  Patients who normally experience high levels of sun exposure, and those with inherent sensitivity to sun, should be warned to exercise caution.  Use of sunscreen products and protective clothing over treated areas is recommended when exposure cannot be avoided.  Weather extremes, such as wind or cold, also may be irritating to patients under treatment with Differin Gel, 0.3%.



Local Cutaneous Reactions


Certain cutaneous signs and symptoms of treatment such as erythema, scaling, dryness, and stinging/burning were reported with use of Differin Gel, 0.3%.  These were most likely to occur during the first four weeks of treatment, were mostly mild to moderate in intensity, and usually lessened with continued use of the medication.  Depending upon the severity of these side effects, patients should be instructed to either use a moisturizer, reduce the frequency of application of Differin Gel, 0.3% or discontinue use.


Avoid contact with the eyes, lips, angles of the nose, and mucous membranes. The product should not be applied to cuts, abrasions, eczematous or sunburned skin.  As with other retinoids, use of "waxing" as a depilatory method should be avoided on skin treated with adapalene.


As Differin Gel has the potential to induce local irritation in some patients, concomitant use of other potentially irritating topical products (medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect and products with high concentrations of alcohol, astringents, spices, or lime) should be approached with caution.



Allergic/ Hypersensitivity Reactions


Reactions characterized by symptoms such as pruritus, face edema, eyelid edema, and lip swelling, requiring medical treatment have been reported during postmarketing use of adapalene. A patient should stop using Differin Gel, 0.3% and consult a doctor if experiencing allergic or anaphylactoid/anaphylactic reactions (e.g., skin rash, pruritus, hives, chest pain, edema, and shortness of breath) during treatment.



Adverse Reactions



Clinical Studies Experience


Because clinical studies are conducted under widely varying conditions, adverse reactions rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice.


In the multi-center, controlled clinical trial, signs and symptoms of local cutaneous irritation were monitored in 258 acne patients who used Differin Gel, 0.3% once daily for 12 weeks.  Of the patients who experienced cutaneous irritation (erythema, scaling, dryness, and/or burning/stinging), the majority of cases were mild to moderate in severity, occurred early in treatment and decreased thereafter.  The incidence of local cutaneous irritation with Differin Gel, 0.3% from the controlled clinical study is provided in the following table:

























Table 1: Physician assessed local cutaneous irritation with Differin Gel
Incidence of Local Cutaneous Irritation with Differin Gel, 0.3% from Controlled Clinical Study

(N = 253*)

Maximum Severity Scores Higher Than Baseline
 MildModerateSevere
Erythema66 (26.1%)33 (13.0%)1 (0.4%)
Scaling110 (43.5%)47 (18.6%)3 (1.2%)
Dryness113 (44.7%)43 (17.0%)2 (0.8%)
Burning/Stinging72 (28.5%)36 (14.2%)9 (3.6%)

* Total number of subjects with local cutaneous data for at least one post-Baseline evaluation.





















Table 2: Patient reported local cutaneous adverse reactions with Differin Gel
 Differin (adapalene) Gel, 0.3%Vehicle Gel
N=258N=134
Related* Adverse Reactions57 (22.1%)6 (4.5%)
     Dry Skin36 (14%)2 (1.5%)
     Skin Discomfort15 (5.8%)0 (0.0%)
     Desquamation4 (1.6%)0 (0.0%)

* Selected adverse reactions defined by investigator as Possibly, Probably or Definitely Related


Related adverse reactions from the controlled clinical trial that occurred in greater than 1% of patients who used Differin Gel, 0.3% once daily included: dry skin (14.0%), skin discomfort (5.8%), pruritus (1.9%), desquamation (1.6%), and sunburn (1.2%).  The following selected adverse reactions occurred in less than 1% of patients: acne flare, contact dermatitis, eyelid edema, conjunctivitis, erythema, pruritus, skin discoloration, rash, and eczema.


In a one-year, open-label safety study of 551 patients with acne who received Differin Gel, 0.3%, the pattern of adverse reactions was similar to the 12-week controlled study.



Postmarketing Experience


The following adverse reactions have been identified during post approval use of adapalene: skin irritation, application site pain, face edema, eyelid edema, lip swelling, and angioedema.  Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate the frequency or establish a causal relationship to drug exposure.



Drug Interactions


Concomitant Topical Medications

As Differin Gel, 0.3% has the potential to induce local irritation in some patients, concomitant use of other potentially irritating topical products (medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol, astringents, spices, or lime) should be approached with caution.  Particular caution should be exercised in using preparations containing sulfur, resorcinol, or salicylic acid in combination with Differin Gel, 0.3%.  If these preparations have been used, it is advisable not to start therapy with Differin Gel, 0.3%, until the effects of such preparations have subsided.


No formal drug-drug interaction studies were conducted with Differin Gel, 0.3%.



USE IN SPECIFIC POPULATIONS



Pregnancy


Teratogenic effects.  Pregnancy Category C.

Retinoids may cause fetal harm, when administered to pregnant women.  Adapalene has been shown to be teratogenic in rats and rabbits when administered orally (see Animal Data below).  There are no adequate and well-controlled studies in pregnant women.  Differin Gel, 0.3% should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.  The safety and efficacy of Differin Gel, 0.3% in pregnancy has not been established.


Human Data


In clinical trials involving Differin Gel, 0.3% in the treatment of acne vulgaris, women of child-bearing potential initiated treatment only after having had a negative pregnancy test and used effective birth control measures during therapy.  However, 6 women treated with Differin Gel, 0.3% became pregnant.  One patient elected to terminate the pregnancy, two patients delivered healthy babies by normal delivery, two patients delivered prematurely and the babies remained in intensive care until reaching a healthy state and one patient was lost to follow-up.


Animal Data


  • No teratogenic effects were seen in rats at oral doses of 0.15 to 5.0 mg/kg/day adapalene representing up to 6 times the maximum recommended human dose (MRHD) based on mg/m² comparisons.  Adapalene has been shown to be teratogenic in rats and rabbits when administered orally at doses ≥ 25 mg/kg representing 32 and 65 times, respectively, the MRHD based on mg/m² comparisons.  Findings included cleft palate, microphthalmia, encephalocele and skeletal abnormalities in the rat and umbilical hernia, exophthalmos and kidney and skeletal abnormalities in the rabbit.

  • Cutaneous teratology studies in rats and rabbits at doses of 0.6, 2.0, and 6.0 mg/kg/day exhibited no fetotoxicity and only minimal increases in supernumerary ribs in both species and delayed ossification in rabbits.  Systemic exposure (AUC0-24h) to adapalene 0.3% gel at topical doses of 6.0 mg/kg/day in rats and rabbits represented 5.7 and 28.7 times, respectively, the exposure in acne patients treated with adapalene 0.3% gel applied to the face, chest and back (2 grams applied to 1000 cm2 of acne involved skin).


Nursing Mothers


It is not known whether adapalene is excreted in human milk.  Because many drugs are excreted in human milk, caution should be exercised when Differin Gel, 0.3% is administered to a nursing woman.



Pediatric Use


Safety and effectiveness have not been established in pediatric patients below the age of 12.



Geriatric Use


Clinical studies of Differin Gel, 0.3% did not include subjects 65 years of age and older to determine whether they respond differently than younger subjects.  Safety and effectiveness in geriatric patients age 65 and above have not been established.



Overdosage


Differin Gel, 0.3% is intended for topical use only.  If the medication is applied excessively, no more rapid or better results will be obtained and marked redness, scaling, or skin discomfort may occur.  Chronic ingestion of the drug may lead to the same side effects as those associated with excessive oral intake of vitamin A.



Differin Description


Differin (adapalene) Gel, 0.3% contains adapalene 0.3% (3 mg/g) in a topical aqueous gel for use in the treatment of acne vulgaris, consisting of carbomer 940, edetate disodium, methylparaben, poloxamer 124, propylene glycol, purified water, and sodium hydroxide.  May contain hydrochloric acid for pH adjustment.


The chemical name of adapalene is 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid.  It is a white to off-white powder, which is soluble in tetrahydrofuran, very slightly soluble in ethanol, and practically insoluble in water.  The molecular formula is C28H28O3 and molecular weight is 412.53.  Adapalene is represented by the following structural formula.




Differin - Clinical Pharmacology



Mechanism of Action


Adapalene binds to specific retinoic acid nuclear receptors but does not bind to cytosolic receptor protein.  Biochemical and pharmacological profile studies have demonstrated that adapalene is a modulator of cellular differentiation, keratinization, and inflammatory processes.   However, the significance of these findings with regard to the mechanism of action of adapalene for the treatment of acne is unknown.



Pharmacodynamics


Clinical pharmacodynamic studies have not been conducted for Differin Gel, 0.3%.



Pharmacokinetics


Systemic exposure of adapalene following topical application of Differin Gel was evaluated in a clinical study. Sixteen acne patients were treated once daily for 10 days with 2 grams of Differin Gel, 0.3% applied to the face, chest and back, corresponding to approximately 2 mg/cm2.  Fifteen patients had quantifiable (LOQ = 0.1 ng/mL) adapalene levels resulting in a mean Cmax of 0.553 ± 0.466 ng/mL on Day 10 of treatment.  The mean AUC0-24hr was 8.37 ± 8.46 ng.h/mL as determined in 15 of the 16 patients on Day 10.  The terminal apparent half-life, determined in 15 of 16 patients, ranged from 7 to 51 hours, with a mean of 17.2 ± 10.2 hours.  Adapalene was rapidly cleared from plasma and was not detected 72 hours after the last application for all but one subject.  Exposure of potential circulating metabolites of adapalene was not measured.  Excretion of adapalene appears to be primarily by the biliary route.


In another clinical study in patients with moderate to moderately severe acne, Differin (adapalene) Gel, 0.3% or Adapalene Gel, 0.1% was applied to the face and optionally to the trunk, once daily for 12 weeks.  Seventy-eight (78) patients had plasma adapalene levels evaluated at Weeks 2, 8, and 12.  Of the 209 plasma samples analyzed, adapalene concentrations were below the limit of detection (LOD = 0.15 ng/mL) of the method in all samples but three.  For the three samples, traces of adapalene below the limit of quantification (LOQ = 0.25 ng/mL) of the method were found.  One of these samples was taken at Week 12 from a male patient treated with Differin Gel, 0.3% who treated the face and the trunk for eight weeks (thereafter, only the face was treated).  The second and third samples were from the Week 2 and 12 visits of a female patient treated with Adapalene Gel, 0.1% who treated only the face for 12 weeks.  In this study, the average daily usage of product was 1 g/day.



Nonclinical Toxicology



Carcinogenesis, Mutagenesis, Impairment of Fertility


Carcinogenicity studies with adapalene have been conducted in mice at topical doses of 0.4, 1.3, and 4.0 mg/kg/day, and in rats at oral doses of 0.15, 0.5, and 1.5 mg/kg/day.  These doses are up to 3 times (mice) and 2 times (rats) in terms of mg/m²/day the potential exposure at the maximum recommended human dose (MRHD), assumed to be 2.5 grams Differin Gel, 0.3%.  In the oral study, increased incidence of benign and malignant pheochromocytomas in the adrenal medullas of male rats was observed.


No photocarcinogenicity studies were conducted.  Animal studies have shown an increased risk of skin neoplasms with the use of pharmacologically similar drugs (e.g., retinoids) when exposed to UV irradiation in the laboratory or to sunlight.  Although the significance of these studies to human use is not clear, patients should be advised to avoid or minimize exposure to either sunlight or artificial UV irradiation sources.


Adapalene did not exhibit mutagenic or genotoxic effects in vitro (Ames test, Chinese hamster ovary cell assay, mouse lymphoma TK assay) and in vivo (mouse micronucleus test).


Reproductive function and fertility studies were conducted in rats administered oral doses of adapalene in amounts up to 20 mg/kg/day (up to 26 times the MRHD based on mg/m² comparisons).  No effects of adapalene were found on the reproductive performance or fertility of the F0 males or females.  There were also no detectable effects on the growth, development and subsequent reproductive function of the F1 offspring.



Clinical Studies


The safety and efficacy of once daily use of Differin Gel, 0.3% for treatment of acne vulgaris were assessed in one 12 week, multi-center, controlled, clinical study, conducted in a total of 653 patients 12 to 52 years of age with acne vulgaris of mild to moderate severity.  All female patients of child-bearing potential enrolled in the study were required to have a negative urine pregnancy test at the beginning of the study and were required to practice a highly effective method of contraception during the study.  Female patients who were pregnant, nursing or planning to become pregnant were excluded from the study.


Patients enrolled in the study were Caucasian (72%), Hispanic (12%), African-American (10%), Asian (3%), and other (2%).  An equal number of males (49.5%) and females (50.5%) enrolled.  Success was defined as "Clear" or "Almost Clear" in the Investigator’s Global Assessment (IGA).  The success rate, mean reduction, and percent reduction in acne lesion counts from Baseline after 12 weeks of treatment are presented in the following table:

























































Table 3: Clinical study primary efficacy results at Week 12
 Differin (adapalene) Gel, 0.3%Adapalene Gel, 0.1%Vehicle Gel
N=258N=261N=134
IGA Success Rate53 (21%)41 (16%)12 (9%)
Inflammatory Lesions   
 Mean Baseline Count27.728.127.2
 Mean Absolute (%) Reduction14.4 (51.6%)13.9 (49.7%)11.2 (40.7%)
Non-inflammatory Lesions   
 Mean Baseline Count39.441.040.0
 Mean Absolute (%) Reduction16.3 (39.7%)15.2 (35.2%)10.3 (27.2%)
Total Lesions   
 Mean Baseline Count67.169.167.2
 Mean Absolute (%) Reduction30.6 (45.3%)29.0 (41.8%)21.4 (33.7%)

HOW SUPPLIED/ STORAGE AND HANDLING


Differin Gel, 0.3% is supplied in the following size.

45g tube – NDC 0299-5918-45


Storage: Store at controlled room temperature 68° to 77°F (20° to 25°C) with excursions permitted between 59° to 86°F (15° to 30°C).  Protect from freezing.  Keep out of reach of children.



Patient Counseling Information



Information for Patients


Patients using Differin Gel, 0.3%, should receive the following information and instructions:


  1. This medication is to be used only as directed by the physician.

  2. Do not use more than the recommended amount and do not apply more than once daily as this will not produce faster results, but may increase irritation.

  3. Apply a thin film of Differin Gel, 0.3% to the entire face and any other affected areas of the skin once daily in the evening, after washing gently with a non-medicated soap.

  4. Avoid contact with the eyes, lips, angles of the nose, and mucous membranes.

  5. Moisturizers may be used if necessary; however, products containing alpha hydroxy or glycolic acids should be avoided.

  6. Exposure of the eye to this medication may result in reactions such as swelling, conjunctivitis, and eye irritation.

  7. This medication should not be applied to cuts, abrasions, eczematous, or sunburned skin.

  8. Wax depilation should not be performed on treated skin due to the potential for skin erosions.

  9. Minimize exposure to sunlight including sunlamps.  Recommend the use of sunscreen products and protective apparel (e.g., hat) when exposure cannot be avoided.

  10. During the early weeks of therapy, an apparent exacerbation of acne may occur.  This may be due to the action of the medication on previously unseen lesions and should not be considered a reason to discontinue therapy.

  11. Contact the doctor if skin rash, pruritus, hives, chest pain, edema, and shortness of breath occurs, as these may be signs of allergy or hypersensitivity.

  12. It is for external use only.

 


 


Marketed by:

GALDERMA LABORATORIES, L.P.

Fort Worth, Texas 76177 USA


Manufactured by:

DPT Laboratories, Ltd.

San Antonio, Texas 78215 USA

GALDERMA is a registered trademark. 

325089-0810


Manufactured by:

G Production Inc.

Baie d’Urfe´, QC, H9X 3S4 Canada

Made in Canada

GALDERMA is a registered trademark.

P51238-1



PACKAGE LABEL



Differin® 0.3

(adapalene)gel, 0.3%


GEL


0.3%


NDC 0299-5918-45


Rx Only


NET WT. 45 g


GALDERMA


For external use only. Not for ophthalmic, oral, or intravaginal use.


Usual dosage: apply a thin film once a day at nighttime to affected areas. See package insert for complete prescribing information.


Each gram contains: adapalene 0.3% (3 mg) in an aqueous gel consisting of carbomer 940, edetate disodium, methylparaben, poloxamer 124, propylene glycol, purified water, and sodium hydroxide. May contain hydrochloric acid for pH adjustment.


Storage: Store at controlled room temperature 68° to 77°F (20° to 25°C) with excursions permitted between 59° to 86°F (15° to 30°C). Protect from freezing.


Marketed by:

GALDERMA LABORATORIES, L.P.

Fort Worth, Texas 76177 USA

Manufactured by:

DPT Laboratories, Ltd.

San Antonio, Texas 78215 USA

GALDERMA is a registered trademark.

www.Differin.com

310125-0107



Differin® 0.3

(adapalene)gel, 0.3%


GEL


0.3%


NDC 0299-5918-45


Rx Only


NET WT. 45 g


GALDERMA


For external use only. Not for ophthalmic, oral, or intravaginal use.


Usual dosage: apply a thin film once a day at nighttime to affected areas. See package insert for complete prescribing information.


Each gram contains: adapalene 0.3% (3 mg) in an aqueous gel consisting of carbomer 940, edetate disodium, methylparaben, poloxamer 124, propylene glycol, purified water, and sodium hydroxide. May contain hydrochloric acid for pH adjustment.


Storage: Store at controlled room temperature 68° to 77°F (20° to 25°C) with excursions permitted between 59° to 86°F (15° to 30°C). Protect from freezing.


Marketed by:

GALDERMA LABORATORIES, L.P.

Fort Worth, Texas 76177 USA

Manufactured by:

G Production Inc.

Baie d’Urfe´, QC, H9X 3S4 Canada

Made in Canada

GALDERMA is a registered trademark.

www.Differin.com

P51241-1









Differin  
adapalene  gel










Product Information
Product TypeHUMAN PRESCRIPTION DRUGNDC Product Code (Source)0299-5918
Route of AdministrationTOPICALDEA Schedule    








Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
Adapalene (ADAPALENE)Adapalene3 mg  in 1 g




















Inactive Ingredients
Ingredient NameStrength
Carbomer Homopolymer Type C 
Edetate Disodium 
Methylparaben 
Propylene Glycol 
Water 
Sodium Hydroxide 
Hydrochloric Acid 
Poloxamer 124 


















Product Characteristics
Color    Score    
ShapeSize
FlavorImprint Code
Contains      














Packaging
#NDCPackage DescriptionMultilevel Packaging
10299-5918-4545 g In 1 TUBENone
20299-5918-022 g In 1 TUBENone










Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
NDANDA02175309/15/2009


Labeler - Galderma Laboratories, L.P. (047350186)









Establishment
NameAddressID/FEIOperations
DPT Laboratories, Ltd.832224526manufacture









Establishment
NameAddressID/FEIOperations
G Production Inc.251676961manufacture
Revised: 02/2012Galderma Laboratories, L.P.

Sunday, 10 October 2010

Biscosal




Biscosal may be available in the countries listed below.


Ingredient matches for Biscosal



Fluocinonide

Fluocinonide is reported as an ingredient of Biscosal in the following countries:


  • Japan

International Drug Name Search

Saturday, 2 October 2010

Euticlavir




Euticlavir may be available in the countries listed below.


Ingredient matches for Euticlavir



Amoxicillin

Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Euticlavir in the following countries:


  • Italy

Clavulanate

Clavulanic Acid potassium (a derivative of Clavulanic Acid) is reported as an ingredient of Euticlavir in the following countries:


  • Italy

International Drug Name Search

Monday, 27 September 2010

Kalcij-folinat Pliva




Kalcij-folinat Pliva may be available in the countries listed below.


Ingredient matches for Kalcij-folinat Pliva



Calcium Folinate

Calcium Folinate is reported as an ingredient of Kalcij-folinat Pliva in the following countries:


  • Bosnia & Herzegowina

  • Croatia (Hrvatska)

International Drug Name Search

Thursday, 23 September 2010

Reluri


Generic Name: guaifenesin and phenylephrine (gwye FEN e sin and FEN il EFF rin)

Brand Names: Aldex G, Aquatab D, Crantex, D-Phen 1000, D-Tab, Deconex, Deconsal II, Deconsal Pediatric, Despec, Donatussin Drops, Duomax, Duraphen 1000, Duraphen II, Duratuss, Dynex LA, ExeTuss, Extendryl G, Fenesin PE IR, Genexa LA, Gentex LA, Gilphex TR, Guaiphen-D 1200, Guaiphen-D 600, Guaiphen-PD, Guiadex PD, Guiatex PE, J-Max, Liquibid D-R, Liquibid-D, Liquibid-PD, Lusonex, Maxiphen, Medent-PE, MontePhen, Mucinex Children's Cold, Mucus Relief Sinus, Mydex, Nariz, Nasex, Nescon-PD, Nexphen PD, Norel EX, PE-Guai, Pendex, Prolex D, Refenesen PE, Reluri, Rescon-GG, Respa-PE, Robitussin Head & Chest Congestion, Simuc, Simuc-GP, Sina-12X, Sinupan, SINUvent PE, Sitrex PD, Sudafed PE Non-Drying Sinus, Sudex, Triaminic Chest & Nasal Congestion, Visonex, Wellbid-D, Xedec, Xedec II, Xpect-PE, Zotex GPX


What is Reluri (guaifenesin and phenylephrine)?

There are many brands and forms of guaifenesin and phenylephrine available and not all brands are listed on this leaflet.


Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.


Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).


The combination of guaifenesin and phenylephrine is used to treat stuffy nose and sinus congestion, and to reduce chest congestion caused by the common cold or flu.


Guaifenesin and phenylephrine may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Reluri (guaifenesin and phenylephrine)?


There are many brands and forms of guaifenesin and phenylephrine available and not all brands are listed on this leaflet.


Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Ask a doctor or pharmacist before using any other cough, cold, or allergy medicine. Guaifenesin and phenylephrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains guaifenesin or phenylephrine.

What should I discuss with my healthcare provider before taking Reluri (guaifenesin and phenylephrine)?


You should not use this medication if you are allergic to guaifenesin or phenylephrine, or to other decongestants, diet pills, stimulants, or ADHD medications. Do not use guaifenesin and phenylephrine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use guaifenesin and phenylephrine before the MAO inhibitor has cleared from your body.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have:



  • heart disease or high blood pressure;




  • diabetes;




  • circulation problems;




  • glaucoma;




  • overactive thyroid; or




  • enlarged prostate or problems with urination.




It is not known if this medication may be harmful to an unborn baby. Do not use this medication without your doctor's advice if you are pregnant. This medication passes into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.


How should I take Reluri (guaifenesin and phenylephrine)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.


Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.


Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Take guaifenesin and phenylephrine with food if it upsets your stomach. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash. Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication. Store at room temperature away from moisture and heat.

What happens if I miss a dose?


Since cough or cold medicine is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, numbness or tingly feeling, dizziness, and feeling restless or nervous.


What should I avoid while taking Reluri (guaifenesin and phenylephrine)?


This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of guaifenesin and phenylephrine. Ask a doctor or pharmacist before using any other cough, cold, or allergy medicine. Guaifenesin and phenylephrine are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains guaifenesin or phenylephrine.

Avoid taking this medication with diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.


Reluri (guaifenesin and phenylephrine) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;




  • severe dizziness, anxiety, restless feeling, or nervousness;




  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;




  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure); or




  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).



Less serious side effects may include:



  • vomiting, upset stomach;




  • warmth, tingling, or redness under your skin;




  • feeling excited or restless (especially in children);




  • sleep problems (insomnia);




  • skin rash or itching;




  • headache; or




  • dizziness.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Reluri (guaifenesin and phenylephrine)?


Ask a doctor or pharmacist if it is safe for you to take guaifenesin and phenylephrine if you are also using any of the following drugs:



  • medicines to treat high blood pressure;




  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or




  • an antidepressant such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan, Silenor), desipramine (Norpramin), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others.



This list is not complete and other drugs may interact with guaifenesin and phenylephrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Reluri resources


  • Reluri Side Effects (in more detail)
  • Reluri Use in Pregnancy & Breastfeeding
  • Reluri Drug Interactions
  • Reluri Support Group
  • 0 Reviews for Reluri - Add your own review/rating


  • Crantex Prescribing Information (FDA)

  • Despec Drops MedFacts Consumer Leaflet (Wolters Kluwer)

  • Entex LA Sustained-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

  • Gentex LA Sustained-Release Tablets (12 Hour) MedFacts Consumer Leaflet (Wolters Kluwer)

  • Guiatex PE Prescribing Information (FDA)

  • Lusonex Controlled-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Rescon-GG Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

  • Sina-12X Suspension MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Reluri with other medications


  • Cough and Nasal Congestion
  • Sinus Symptoms


Where can I get more information?


  • Your pharmacist can provide more information about guaifenesin and phenylephrine.

See also: Reluri side effects (in more detail)


Wednesday, 22 September 2010

Alphapen




Alphapen may be available in the countries listed below.


Ingredient matches for Alphapen



Ampicillin

Ampicillin sodium salt (a derivative of Ampicillin) is reported as an ingredient of Alphapen in the following countries:


  • Mexico

International Drug Name Search

Eludril




Eludril may be available in the countries listed below.


Ingredient matches for Eludril



Chlorhexidine

Chlorhexidine is reported as an ingredient of Eludril in the following countries:


  • Tunisia

Chlorhexidine digluconate (a derivative of Chlorhexidine) is reported as an ingredient of Eludril in the following countries:


  • Belgium

  • Luxembourg

International Drug Name Search

Tuesday, 21 September 2010

Hydrokortison CCS




Hydrokortison CCS may be available in the countries listed below.


Ingredient matches for Hydrokortison CCS



Hydrocortisone

Hydrocortisone is reported as an ingredient of Hydrokortison CCS in the following countries:


  • Sweden

International Drug Name Search

Monday, 20 September 2010

Ampisur




Ampisur may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Ampisur



Ampicillin

Ampicillin trihydrate (a derivative of Ampicillin) is reported as an ingredient of Ampisur in the following countries:


  • Poland

Colistin Sulfate

Colistin sulfate (a derivative of Colistin) is reported as an ingredient of Ampisur in the following countries:


  • Poland

International Drug Name Search

Sunday, 19 September 2010

Tétrazépam Winthrop




Tétrazépam Winthrop may be available in the countries listed below.


Ingredient matches for Tétrazépam Winthrop



Tetrazepam

Tetrazepam is reported as an ingredient of Tétrazépam Winthrop in the following countries:


  • France

International Drug Name Search

Tuesday, 7 September 2010

Diapro




Diapro may be available in the countries listed below.


Ingredient matches for Diapro



Gliclazide

Gliclazide is reported as an ingredient of Diapro in the following countries:


  • Bangladesh

  • Myanmar

International Drug Name Search

Sunday, 5 September 2010

Acetylsalicylic Acid




In some countries, this medicine may only be approved for veterinary use.


In the US, Acetylsalicylic Acid is a member of the following drug classes: platelet aggregation inhibitors, salicylates and is used to treat Angina, Angina Pectoris Prophylaxis, Ankylosing Spondylitis, Antiphospholipid Syndrome, Aseptic Necrosis, Back Pain, Fever, Heart Attack, Ischemic Stroke, Ischemic Stroke - Prophylaxis, Juvenile Rheumatoid Arthritis, Kawasaki Disease, Myocardial Infarction - Prophylaxis, Niacin Flush, Osteoarthritis, Pain, Prosthetic Heart Valves, Prosthetic Heart Valves - Mechanical Valves, Revascularization Procedures - Prophylaxis, Rheumatic Fever, Rheumatoid Arthritis, Sciatica, Systemic Lupus Erythematosus and Thromboembolic Stroke Prophylaxis.

Scheme

Ph. Eur.

ATC (Anatomical Therapeutic Chemical Classification)

A01AD05,B01AC06,N02BA01

CAS registry number (Chemical Abstracts Service)

0000050-78-2

Chemical Formula

C9-H8-O4

Molecular Weight

180

Therapeutic Categories

Analgesic, antipyretic and anti-inflammatory agent

Antiplatelet agent, irreversible cyclo-oxygenase inhibitor

Non-steroidal anti-inflammatory drug, NSAID

Chemical Names

2-Acetoxybenzoic acid

2-Carboxyphenyl acetate

Benzoic acid, 2-(acetyloxy)-

Foreign Names

  • Acidum acetylsalicylicum (Latin)
  • Acetylsalicylsäure (German)
  • Acide acétylsalicylique (French)
  • Ácido acetylsalicílico (Spanish)

Generic Names

  • Acide acétylsalicylique (OS: DCF)
  • Aspirin (OS: BAN, JAN)
  • ASA (IS)
  • ASS (IS)
  • Acetylsalicylic Acid (PH: Ph. Eur. 6, JP)
  • Acétylsalicylique (acide) (PH: Ph. Eur. 6)
  • Acetylsalicylsäure (PH: Ph. Eur. 6)
  • Acidum acetylsalicylicum (PH: Ph. Int. 4, Ph. Eur. 6)
  • Aspirin (PH: BP 2010, USP 32, JP XV)
  • Aspirin Lysine (OS: BANM)
  • DL-Lysin $IO$R-acetylsalicylat (IS)
  • DL-Lysinmono (IS: acetylsalicylat)
  • DL-Lysine (Acétylsalicylate de) (PH: Ph. Franç. Xe édit)

Brand Names

  • A 20 (veterinary use)
    Vetos-Farma, Poland


  • A.A.S. 500
    GlaxoSmithKline, Portugal


  • A.S.A.
    Apex, Bangladesh


  • AAS
    Sanofi-Aventis, Argentina; Sanofi-Aventis S.A., Spain


  • Ac Cod PCH (Acetylsalicylic Acid and Codeine)
    Pharmachemie, Netherlands


  • Ac Cod Ratiopharm (Acetylsalicylic Acid and Codeine)
    ratiopharm, Netherlands


  • Acard
    Polfa Warszawa, Lithuania; Polfa Warszawa, Poland


  • Acenterine
    Nycomed, Belgium; Nycomed, Luxembourg


  • Acepral
    Saidal, Algeria


  • Acesal
    Nycomed, Germany


  • Acesan
    Sun-Farm, Poland


  • Acetilsalicilo rugstis
    Liuks, Lithuania


  • Acetilsalicilskabe
    Stirolbiofarm, Latvia


  • Acetisal
    Galenika, Serbia; Galenika, Serbia


  • Acetosal
    Rekah, Israel


  • Acetylin
    Milve, Bulgaria


  • Acetylsalicylic Acid
    Biogal, Ethiopia; MidWest, New Zealand


  • Acetylsalicylsaure-RPM
    ratiopharm, Luxembourg


  • Acetylsalicylzuur A
    Apothecon, Netherlands


  • Acetylsalicylzuur Actavis
    Actavis, Netherlands


  • Acetylsalicylzuur CF
    Centrafarm, Netherlands


  • Acetylsalicylzuur EB
    Eurobase, Netherlands


  • Acetylsalicylzuur HTP
    Healthypharm, Netherlands


  • Acetylsalicylzuur Katwijk
    Apotex Europe, Netherlands


  • Acetylsalicylzuur Meda
    Meda, Netherlands


  • Acetylsalicylzuur Merck
    Mylan, Netherlands


  • Acetylsalicylzuur PCH
    Pharmachemie, Netherlands


  • Acetylsalicylzuur ratiopharm
    ratiopharm, Netherlands


  • Acetylsalicylzuur Sandoz
    Sandoz, Netherlands


  • Acetylsalicylzuur
    Etos, Netherlands; Eurobase, Netherlands


  • Acetylsalicylzuur (veterinary use)
    Eurovet, Netherlands


  • Acetysal
    Actavis, Bulgaria; Actavis, Georgia; Jugoremedija, Serbia


  • Acid Acetilsalicilic Tamponat
    Gedeon Richter, Romania; Santa, Romania


  • Acid Acetilsalicilic
    Magistra, Romania; Zentiva, Romania


  • Acido Acetil Salicilico AZ
    AZ Pharma, Colombia


  • Acido Acetilsalicilico + Acido Ascorbico Coop (Acetylsalicylic Acid and Ascorbic Acid)
    Coop Italia, Italy


  • Acido Acetilsalicilico + Vitamina C Angenerico (Acetylsalicylic Acid and Ascorbic Acid)
    Angenerico, Italy


  • Acido Acetilsalicilico + Vitamina C Mylan (Acetylsalicylic Acid and Ascorbic Acid)
    Mylan, Italy


  • Acido Acetilsalicilico Afom
    AFOM, Italy


  • Acido Acetilsalicilico Angenerico
    Angenerico, Italy


  • Acido Acetilsalicilico Farmacologico
    Farmacologico, Italy


  • Acido Acetilsalicilico Nova Argentia
    Nova Argentia, Italy


  • Acido Acetilsalicílico Ratiopharm
    Ratiopharm, Portugal


  • Acido Acetilsalicilico
    Bestpharma, Chile; Labot, Peru; Pasteur, Chile; Spefar, Venezuela


  • Acido Acetilsalicilico (veterinary use)
    Doxal, Italy


  • Acidum Acetylsalicylicum Darnica
    Darnitsa, Georgia


  • Acidum Acetylsalicylicum
    Batfarma, Georgia


  • Aciprin CV
    ACI, Bangladesh


  • Actipiril
    Confar, Portugal


  • Acyflox (Acetylsalicylic Acid and Ascorbic Acid)
    Pliva, Spain


  • Acylcoffin (Acetylsalicylic Acid andCaffeine)
    Zentiva, Slovakia


  • Acylpyrin Effervescens
    Herbacos, Czech Republic


  • Acylpyrin+C (Acetylsalicylic Acid andAscorbic Acid)
    Herbacos, Slovakia


  • Acylpyrin
    Herbacos, Czech Republic; Herbacos, Slovakia


  • Adalat XL Plus (Acetylsalicylic Acid and Nifedipine)
    Bayer, Canada


  • Adiprin
    Advanced Pharmaceuticals, Bahrain


  • Adiro
    Bayer, Spain


  • Aggrenox EuroPharmaDK (Acetylsalicylic Acid and Dipyridamole)
    Boehringer Ingelheim, Denmark


  • Aggrenox Orifarm (Acetylsalicylic Acid and Dipyridamole)
    Boehringer Ingelheim, Denmark


  • Aggrenox Paranova (Acetylsalicylic Acid and Dipyridamole)
    Boehringer Ingelheim, Denmark


  • Aggrenox (Acetylsalicylic Acid and Dipyridamole)
    Boehringer Ingelheim, Belgium; Boehringer Ingelheim, Canada; Boehringer Ingelheim, Germany; Boehringer Ingelheim, Greece; Boehringer Ingelheim, Croatia (Hrvatska); Boehringer Ingelheim, Indonesia; Boehringer Ingelheim, Italy; Boehringer Ingelheim, Poland; Boehringer Ingelheim, Russian Federation; Boehringer Ingelheim, Slovakia; Boehringer Ingelheim, United States; Boehringer Ingelheim, Vietnam


  • Albyl minor
    Recip, Sweden


  • Albyl-E
    Nycomed, Norway


  • Albyl-Selters
    Leo, Egypt


  • Alexoprine
    Alexandria Co., Egypt


  • Alfacor
    Generifar, Nicaragua


  • Algo-Bebe
    Lokman, Turkey


  • Algopirina (Acetylsalicylic Acid and Paracetamol)
    Pielle Farmaceutici, Italy


  • Alka Seltzer
    Bayer, Austria; Bayer, Belgium; Bayer, Bulgaria; Bayer, Switzerland; Bayer, Colombia; Bayer, Czech Republic; Bayer, Estonia; Bayer, Spain; Bayer, Georgia; Bayer, Hungary; Bayer, Israel; Bayer, Iceland; Bayer, Italy; Bayer, Lithuania; Bayer, Latvia; Bayer, Netherlands; Bayer, Poland; Bayer, Portugal; Bayer, Romania; Bayer, Russian Federation; Bayer, Singapore; Bayer, United States; Bayer Animal Health, Luxembourg; Bayer Consumer Health Care, Ethiopia; Bayer Santé Familiale, France


  • Alka-Prim
    Polpharma, Poland; Polpharma, Russian Federation


  • Alka-Seltzer
    Bayer, Sweden


  • Alka-Seltzer Classic
    Bayer, Germany


  • Alka-Selzer (Acetylsalicylic Acid and Sodium Bicarbonate)
    Bayer, Canada


  • Alprin
    Eipico, Egypt


  • Amavita ASS + Vit. C (Acetylsalicylic Acid and Ascorbic Acid)
    Amavita Health Care, Switzerland


  • Amisprin
    Amico, Bangladesh


  • Anbol
    Galenika, Serbia


  • Andol
    Pliva, Bosnia & Herzegowina; Pliva, Croatia (Hrvatska); Pliva, Serbia; Pliva, Slovenia


  • Andol (Acetylsalicylic Acid and Ascorbic Acid)
    Pliva, Croatia (Hrvatska)


  • Angettes
    Bristol-Myers Squibb, United Kingdom


  • Angiprin
    Rephco, Bangladesh


  • Anivet (Acetylsalicylic Acid and Oxytetracycline, Sulfamerazine, Sulfadimidine (veterinary use))
    aniMedica, Germany


  • Anopyrin
    Slovakofarma, Czech Republic; Zentiva, Bulgaria; Zentiva, Slovakia


  • Antalyre
    Europhta, France


  • APC Apotex (Acetylsalicylic Acid and Paracetamol)
    Apotex Europe, Netherlands


  • APC Leidapharm (Acetylsalicylic Acid and Paracetamol)
    Leidapharm, Netherlands


  • APC Marel (Acetylsalicylic Acid and Paracetamol)
    Marel, Netherlands


  • APC Sameko (Acetylsalicylic Acid and Paracetamol)
    Sameko, Netherlands


  • APC-ASA
    Apotex, Canada


  • Aptor
    Nicholas, Indonesia


  • ASA 50
    German Remedies, India


  • ASA 50 (veterinary use)
    Doxal, Italy


  • ASA Atid
    Dexcel, Germany


  • ASA Grindeks
    Grindeks, Estonia; Grindeks, Latvia


  • ASA Lannacher
    Lannacher, Latvia


  • ASA MK
    MK, Colombia


  • Asa Mylan
    Mylan, Belgium


  • ASA
    ExtractumPharma, Hungary; German Remedies, India


  • Asaflow
    Nycomed, Belgium; Sandipro, Luxembourg


  • Asaltec
    Polfa Warszawa, Poland


  • Asaprin
    Helcor, Romania


  • Asaprol
    Leti, Venezuela


  • Asasantin Retard (Acetylsalicylic Acid and Dipyridamole)
    Boehringer Ingelheim, Austria; Boehringer Ingelheim, Denmark; Boehringer Ingelheim, Ireland; Boehringer Ingelheim, Sweden; Boehringer Ingelheim, Slovenia; Boehringer Ingelheim, South Africa


  • Asasantin (Acetylsalicylic Acid and Dipyridamole)
    Boehringer Ingelheim, Australia; Boehringer Ingelheim, Switzerland; Boehringer Ingelheim, Finland; Boehringer Ingelheim, United Kingdom; Boehringer Ingelheim, Netherlands; Dr. Fisher, Netherlands; Euro, Netherlands; Medcor, Netherlands


  • Asasantine LP (Acetylsalicylic Acid and Dipyridamole)
    Boehringer Ingelheim, France


  • Asatab
    Odan, Canada


  • ASA-Tabs
    Streuli Pharma, Switzerland


  • Asawin
    Sanofi-Aventis, Colombia; Sanofi-Aventis, Ecuador


  • Ascalcin (Acetylsalicylic Acid and Calcium Lactogluconate)
    Polfa Lódz, Poland


  • Ascard
    Atco Laboratories, Ethiopia


  • Ascardia
    Pharos, Indonesia


  • Ascodan (Acetylsalicylic Acid and Codeine Phosphate)
    Polpharma, Poland


  • Ascopir (veterinary use)
    VAAS, Italy


  • Ascosal (Acetylsalicylic Acid and Ascorbic Acid)
    Grossmann, Oman


  • Ascriptin
    Aventis, Israel; Novartis, United States


  • Asinpirine
    I.E. Ulagay, Turkey


  • Ask pH8
    Habit, Serbia


  • Aspec
    PSM, New Zealand


  • Aspecardum
    Stirolbiofarm, Latvia


  • Aspegic
    Sanofi Winthrop, Bulgaria; Sanofi-Aventis, Oman; Sanofi-Synthelabo, Ghana; Sanofi-Synthelabo, Kenya; Sanofi-Synthelabo, Nigeria; Sanofi-Synthelabo, Tanzania; Sanofi-Synthelabo, Uganda


  • Aspenter
    Terapia, Romania


  • Aspergum
    Heritage, United States; Schering-Plough, United States


  • Asperivo
    Rivopharm, Switzerland


  • Aspetin Adipharm
    Adipharm, Bulgaria


  • Asphanate
    Nakakita Yakuhin, Japan


  • Aspic
    LNK international, Bulgaria


  • Aspicard
    Rowe, Dominican Republic


  • Aspicor
    Fampharm, Serbia; SM Pharma, Venezuela


  • Aspi-Cor
    Health Products, Bahrain


  • Aspicot
    Concept, India


  • Aspiglicina (Acetylsalicylic Acid and Glycine)
    Antonetto, Italy


  • Aspil (veterinary use)
    Mavlab, Australia


  • Aspilets
    Imperial, Philippines; Medifarma, Indonesia; UAP, Indonesia; United, Myanmar


  • Aspilet-Thrombo
    United Pharma, Vietnam


  • Aspimag (Acetylsalicylic Acid and Magnedium Oxide)
    Espefa, Poland


  • Aspimason
    Arion, Peru


  • Aspimax
    Laropharm, Romania


  • Aspin-100
    Cipla, Sri Lanka


  • Aspinal
    Münir Sahin, Turkey


  • Aspinat
    Otechestvennye Lekarstva, Russian Federation


  • Aspinat Cardio
    Valens, Russian Federation


  • Aspirem
    Remedica, Jordan; Remedica, Malta; Remedica, Sudan; Remedica, Yemen


  • Aspirin Activ (Acetylsalicylic Acid and Caffeine)
    Bayer, Poland


  • Aspirin Adult
    Geri-Care, United States; Magno-Humphries, United States


  • Aspirin Akut
    Bayer, Austria


  • Aspirin Bayer
    Bayer, Singapore; Bayer Healthcare LLC, United States; Bayer Schering, Indonesia; Bayer Yakuhin, Japan


  • Aspirin C (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer, Finland; Bayer, Poland; Bayer, Russian Federation


  • Aspirin Cardio
    Bayer, Switzerland; Bayer, Georgia; Bayer, Russian Federation; Bayer, Singapore


  • Aspirin Children's
    AmerisourceBergen, United States; Cardinal Health, United States; Chain Drug, United States; Eckerd, United States; Major, United States; PDK, United States; Qualitest, United States; Rugby, United States; URL, United States


  • Aspirin Complex (Acetylsalicylic Acid and Pseudoephedrine)
    Bayer, Austria


  • Aspirin Delayed Release Tablets
    Time-Cap, United States; United Research, United States


  • Aspirin Dexcel
    Dexcel, United Kingdom


  • Aspirin Direct
    Bayer, Bosnia & Herzegowina


  • Aspirin Domesco
    Domesco, Vietnam


  • Aspirin for Children
    Geri-Care, United States


  • Aspirin plus C (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer, Slovenia


  • Aspirin Protect
    Bayer, Austria; Bayer, Bosnia & Herzegowina; Bayer, Bulgaria; Bayer, Czech Republic


  • Aspirin Suppositories
    Paddock, United States


  • Aspirin+C (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer, Austria


  • Aspirin
    AmerisourceBergen, United States; Bayer, United Arab Emirates; Bayer, Austria; Bayer, Bosnia & Herzegowina; Bayer, Bahrain; Bayer, Canada; Bayer, Switzerland; Bayer, Czech Republic; Bayer, Germany; Bayer, Denmark; Bayer, Estonia; Bayer, Egypt; Bayer, Finland; Bayer, Georgia; Bayer, Greece; Bayer, Croatia (Hrvatska); Bayer, Hungary; Bayer, Israel; Bayer, Iran; Bayer, Jordan; Bayer, Kenya; Bayer, Kuwait; Bayer, Lebanon; Bayer, Lithuania; Bayer, Latvia; Bayer, Malta; Bayer, Nigeria; Bayer, Norway; Bayer, Oman; Bayer, Poland; Bayer, Qatar; Bayer, Romania; Bayer, Serbia; Bayer, Russian Federation; Bayer, Saudi Arabia; Bayer, Sudan; Bayer, Sweden; Bayer, Slovenia; Bayer, Slovakia; Bayer, Taiwan; Bayer Consumer Health Care, Ethiopia; Biopharm, Georgia; Cardinal Health, United States; Galpharm - Perrigo, Malta; Herron, Bahrain; International Generics, Ethiopia; Medicine Shoppe, United States; PDK, United States; Qualitest, United States; Teva USA, United States; Wallis, Malta


  • Aspirin Complex (Acetylsalicylic Acid and Pseudoephedrine)
    Bayer, Switzerland; Bayer, Germany; Bayer, Croatia (Hrvatska)


  • Aspirin forte (Acetylsalicylic Acid and Caffeine)
    Bayer, Germany


  • Aspirin Night Time (Acetylsalicylic Acid and Methocarbamol)
    Bayer, Canada


  • Aspirin plus C (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer, Germany; Bayer, Croatia (Hrvatska)


  • Aspirin-C (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer, Switzerland


  • Aspirina Biocrom
    Biocrom, Argentina


  • Aspirina C (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer, Spain


  • Aspirina Cardiologica
    Ethical, Dominican Republic


  • Aspirina Fabra
    Fabra, Argentina


  • Aspirina Fecofar
    Fecofar, Argentina


  • Aspirina Gervasi
    Gervasi, Spain


  • Aspirina Plus (Acetylsalicylic Acid and Caffeine)
    Bayer, Spain


  • Aspirina Prevent
    Bayer, Brazil


  • Aspirina Protect
    Bayer, Mexico


  • Aspirina Vent-3
    Vent-3, Argentina


  • Aspirina
    Bayer, Chile; Bayer, Colombia; Bayer, Ecuador; Bayer, Spain; Bayer, Italy; Bayer, Peru; Bayer, Portugal; Benitol, Argentina; Benitol, Argentina; Gezzi, Argentina; Klonal, Argentina


  • Aspirina (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer, Italy


  • Aspirine 500 mg Vitamine C Oberlin (Acetylsalicylic Acid and Ascorbic Acid)
    UPSA, France


  • Aspirine Biotic
    Saidal, Algeria


  • Aspirine du Rhône
    Bayer Santé Familiale, France


  • Aspirine Merck Médication Familiale
    Mylan, France


  • Aspirine pH8
    Meda, France


  • Aspirine Protect
    Bayer, Netherlands; Bayer Santé, France; Euro, Netherlands; Medcor, Netherlands; STC, Netherlands


  • Aspirine UPSA
    Bristol-Myers Squibb, Burkina Faso; Bristol-Myers Squibb, Benin; Bristol-Myers Squibb, Congo; Bristol-Myers Squibb, Cote D'ivoire; Bristol-Myers Squibb, Cameroon; Bristol-Myers Squibb, Algeria; Bristol-Myers Squibb, France; Bristol-Myers Squibb, Gabon; Bristol-Myers Squibb, Guinea; Bristol-Myers Squibb, Madagascar; Bristol-Myers Squibb, Mali; Bristol-Myers Squibb, Mauritania; Bristol-Myers Squibb, Niger; Bristol-Myers Squibb, Senegal; Bristol-Myers Squibb, Chad; Bristol-Myers Squibb, Togo; Bristol-Myers Squibb, Zaire


  • Aspirine UPSA Vitaminée C (Acetylsalicylic Acid and Ascorbic Acid)
    UPSA, France


  • Aspirine
    Bayer, Belgium; Bayer, Netherlands; Bayer Animal Health, Luxembourg; Bristol-Myers Squibb, Tunisia; Euro, Netherlands; Medcor, Netherlands; Saiph, Tunisia; Siphat, Tunisia; STC, Netherlands


  • Aspirine (veterinary use)
    Coophavet, France


  • Aspirine C (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer, Belgium


  • Aspirine Duo (Acetylsalicylic Acid and Caffeine)
    Bayer, Belgium


  • Aspirinetas
    Bayer, Argentina


  • Aspirinetta
    Bayer, Italy


  • Aspirisucre
    Arkopharma, France


  • Asprim
    Magnachem, Dominican Republic


  • Aspro Vitamine C (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer Santé Familiale, France


  • Aspro
    Bayer, Switzerland; Bayer, Italy; Bayer, Netherlands; Bayer, New Zealand; Bayer Animal Health, Luxembourg; Bayer Consumer Care, Australia; Bayer Santé Familiale, France; Beta Health Care, Ethiopia; Klosterfrau, Austria; Nicholas, Ethiopia


  • Aspro (Acetylsalicylic Acid and Ascorbic Acid)
    Bayer, Italy


  • Asproaccel (Acetylsalicylic Acid and Caffeine)
    Bayer Santé Familiale, France


  • Asprocard (Acetylsalicylic Acid and Aminoacetic Acid)
    Medicofarma, Poland


  • Asprocol (Acetylsalicylic Acid and Aminoacetic Acid)
    ICN, Poland


  • Asprovit
    Vitale, Estonia


  • ASS + C -1A Pharma (Acetylsalicylic Acid and Ascorbic Acid)
    1A Pharma, Germany


  • ASS + C Hexal (Acetylsalicylic Acid and Ascorbic Acid)
    Hexal, Austria; Hexal, Germany


  • ASS + C-ratiopharm (Acetylsalicylic Acid and Ascorbic Acid)
    Ratiopharm, Germany


  • ASS 1A Pharma
    1A Pharma, Germany


  • ASS AbZ
    AbZ, Germany


  • ASS AL
    Aliud, Germany


  • ASS Atid
    Dexcel, Germany


  • ASS axcount
    Axcount, Germany


  • ASS Cardio Spirig
    Spirig Pharma, Switzerland


  • ASS elac
    AWD.pharma, Germany; Teva, Germany


  • ASS gamma
    Wörwag Pharma, Germany; Wörwag Pharma, Latvia


  • ASS Genericon
    Genericon, Austria


  • ASS Heumann
    Heumann, Germany


  • ASS Hexal
    Hexal, Austria; Hexal, Germany


  • ASS Sandoz
    Sandoz, Germany


  • ASS Stada
    Stada, Germany


  • ASS TAD
    TAD, Germany


  • ASS Teva
    Teva, Germany


  • ASS+C 1A Pharma (Acetylsalicylic Acid and Ascorbic Acid)
    1A Pharma, Austria; 1A Pharma, Germany


  • Assa
    Farmindustria, Peru


  • ASS-CT
    CT Arzneimittel, Germany


  • ASS-Isis
    Actavis, Germany


  • ASS-ratiopharm
    Ratiopharm, Austria; Ratiopharm, Germany


  • Astika
    Ikapharmindo, Indonesia


  • Astrix
    Hospira, Singapore; Mayne, Hong Kong; Mayne Pharma International, Australia; Teva, Hungary


  • Ataspin
    Atabay, Turkey


  • Aterosyn
    Quilab, Peru


  • Azacard
    Oftalmi, Venezuela


  • Babyprin
    Pfizer, Turkey


  • Bamyl
    AstraZeneca, China; Meda, Sweden


  • Bamyl koffein (Acetylsalicylic Acid and Caffeine)
    Meda, Sweden


  • Bassamin
    Taiyo Pharmaceutical, Japan


  • Bayaspirin
    Bayer Schering, China; Bayer Yakuhin, Japan


  • Bayaspirina
    Bayer, Argentina


  • Bayer Aspirin Cardio
    Bayer Consumer Care, South Africa


  • Bayer Aspirin
    Bayer, Philippines; Bayer, Thailand; Bayer, United States; Bayer Consumer Care, Australia; Bayer Consumer Care, South Africa; Fresenius Kabi, Ethiopia


  • Belosalic (Acetylsalicylic Acid and Bethametasone)
    Belupo, Slovenia


  • Bestpirin
    Polfa Kutno, Poland


  • Be-Tabs Aspirin
    Be-Tabs Pharmaceuticals, South Africa


  • Bioplak
    Ern, Spain


  • Blaqueta
    Life, Ecuador


  • Bodrexin
    Bode, Indonesia; Tempo Scan Pacific, Indonesia


  • Bokey
    Yung Shin, Singapore


  • Bospyrin
    Bosnalijek, Bosnia & Herzegowina


  • Boxazin plus C (Acetylsalicylic Acid and Ascorbic Acid)
    Boehringer Ingelheim, Germany


  • Buffered Pirin
    Pennex, Israel


  • Bufferin
    Bristol-Myers Squibb, Oman; Bristol-Myers Squibb, Peru; Bristol-Myers Squibb, United States; Lion, Japan; Novartis, Greece


  • Cafiaspirina (Acetylsalicylic Acid and Caffeine)
    Bayer, Spain


  • Caid
    Jayson, Bangladesh


  • Calcipiryna (Acetylsalicylic Acid and Calcium Carbonate)
    Polpharma, Poland


  • Calmante Vitaminado Rinver (Acetylsalicylic Acid and Thiamine)
    Monik, Spain


  • Caprin
    Pinewood, Ireland


  • CardiASK
    Canonpharma, Russian Federation


  • Cardio Aliv
    LCG, Peru


  • Cardio
    Dexcel, United Kingdom


  • Cardioaspirin
    Bayer, Italy; Bayer Schering, Indonesia


  • Cardioaspirina
    Bayer, Argentina; Bayer, Chile; Bayer, Colombia; Bayer, Ecuador; Bayer, Peru; Bayer, Peru


  • Cardioaspirine
    Bayer, Belgium; Bayer Animal Health, Luxembourg


  • Cardiofil (Acetylsalicylic Acid and Magnesium Oxide)
    Filofarm, Poland


  • Cardionil
    Ariston, Ecuador


  • Cardiopirin
    Colfarm, Poland; Dexcel, Israel; Lannacher, Serbia; PharmaSwiss, Croatia (Hrvatska); PharmaSwiss, Slovenia


  • Cardioton
    Farpasa, Peru


  • Cardiphar
    Teva, Belgium


  • Cardipirina
    Zuoz, Venezuela


  • Cardiprin
    Reckitt Benckiser, Australia; Reckitt Benckiser, Sri Lanka; Reckitt Benckiser, New Zealand; Reckitt Benckiser, Singapore; Reckitt Benckiser, Thailand


  • Cardopyrin
    Gaco, Bangladesh


  • Carin (Acetylsalicylic Acid and Ascorbic Acid)
    FederFARMA.CO, Italy


  • Carisoprodol and Aspirin (Acetylsalicylic Acid and Carisoprodol)
    Actavis, United States; Concord, United States; Par, United States; Sandoz, United States


  • Carnyl Acetylsalicylsyre
    Nycomed, Denmark


  • Cartia
    GlaxoSmithKline, Hong Kong; GlaxoSmithKline, Israel; GlaxoSmithKline Consumer Healthcare, Australia; GlaxoSmithKline Consumer Healthcare, New Zealand; Lusofarmaco, Portugal


  • Carva
    Square, Bangladesh


  • Chefarine (Acetylsalicylic Acid and Paracetamol)
    Chefaro, Netherlands


  • Coated Aspirin
    Bayer, Canada


  • Coco Scalp
    AFT, New Zealand


  • Codis (Acetylsalicylic Acid and Codeine)
    Reckitt Benckiser, Ireland


  • Codral (Acetylsalicylic Acid and Codeine)
    GlaxoSmithKline, Australia


  • Coffepirine (Acetylsalicylic Acid and Caffeine)
    Marcmed, Poland


  • Contra-Schmerz plus (Acetylsalicylic Acid and Caffeine)
    Wild, Switzerland


  • Contrexyn (Acetylsalicylic Acid and Glycine)
    Supra Ferbindo, Indonesia


  • Cor
    Pascual, Philippines


  • Cor-As
    Zdravlje, Serbia


  • Cor-Asa
    Dubonp, Peru


  • Cor-Aspi
    Corfarma, Peru


  • Coraspin
    Bayer, Turkey


  • Cortaba (Acetylsalicylic Acid and Methylprednisolone (veterinary use))
    Pharmacia & Upjohn vet, United States


  • Cortal
    GlaxoSmithKline, Philippines


  • Desenfriolito
    Schering-Plough, Argentina


  • Dextropirine (veterinary use)
    Laboratoires Biové, France


  • Diprosalic (Acetylsalicylic Acid and Betamethasone)
    Schering-Plough, Finland; Schering-Plough, Italy


  • Disgren
    Pasteur, Chile


  • Disperin
    Orion, Estonia; Orion, Finland


  • Dispril
    ARIS, Turkey; Reckitt & Colman, Oman; Reckitt Benckiser, Belgium; Reckitt Benckiser, Luxembourg; Reckitt Benckiser, Norway


  • Disprin Plus (Acetylsalicylic Acid and Codeine)
    Reckitt Benckiser, South Africa


  • Disprin
    Reckitt Benckiser, Australia; Reckitt Benckiser, Bangladesh; Reckitt Benckiser, Ethiopia; Reckitt Benckiser, Hong Kong; Reckitt Benckiser, Ireland; Reckitt Benckiser, New Zealand; Reckitt Benckiser, Singapore; Reckitt Benckiser, South Africa; Riyadh, Bahrain


  • Doloprim (Acetylsalicylic Acid and Caffein)
    Galenus, Poland


  • Dolviran (Acetylsalicylic Acid and Codeine)
    Meda, Germany; Meda, Luxembourg


  • Dominal
    Chile, Chile


  • DuoCover (Acetylsalicylic Acid and Clopidogrel)
    Bristol-Myers Squibb, Australia; Bristol-Myers Squibb, Germany


  • Duofilm (Acetylsalicylic Acid and Lactic Acid)
    Stiefel, New Zealand


  • Duokapton (Acetylsalicylic Acid and Paracetamol)
    Strallhofer, Austria


  • DuoPlavin (Acetylsalicylic Acid and Clopidogrel)
    Sanofi-Aventis, Germany


  • Dusil
    Alpharma, Singapore


  • Dynasprin
    USV, India


  • EAC (Acetylsalicylic Acid and Ascorbic Acid)
    Toyama Kagaku, Japan


  • Easprin
    Rosedale, United States


  • Ecopirin
    Abdi Ibrahim, Turkey


  • Ecoprin
    Sam-On, Israel


  • Ecosprin
    Acme, Bangladesh; Sidmak, India


  • Ecotrin
    GlaxoSmithKline, Chile; GlaxoSmithKline, Colombia; GlaxoSmithKline, Peru; GlaxoSmithKline, Taiwan; GlaxoSmithKline, United States; Goldshield, Australia; Pharmafrica, South Africa; Schering-Plough, Argentina


  • Egozite Cradle Cap Lotion
    Ego, New Zealand


  • Encopirin
    Omega Rex, Poland


  • Encopyrin
    Jayson, Bangladesh


  • Equagesic (Acetylsalicylic Acid and Meprobamate)
    Caraco, United States


  • Eras
    Unimed & Unihealth, Bangladesh


  • Ethics Aspirin
    Multichem, New Zealand


  • Eudorlin (Acetylsalicylic Acid and Caffeine)
    Berlin-Chemie, Germany


  • Europirin T
    Europharm, Romania


  • Europirin
    Europharm, Romania


  • Famoter
    Tsuruhara Seiyaku, Japan


  • Farmasal
    Fahrenheit, Indonesia


  • Febrisan ASS
    Scheffler, Germany


  • Fibrex (Acetylsalicylic Acid and Paracetamol)
    Berlin-Chemie, Germany


  • Flamasacard
    Abbeyvet, United Kingdom


  • Fluicor
    Maver, Chile


  • Fusen
    Chin Teng, Taiwan


  • Gacopyrin
    Gaco, Bangladesh


  • Galocard
    Galenus, Poland


  • Ganadol (veterinary use)
    Fatro, Italy


  • Genacote
    Teva USA, United States


  • Genasprin
    Sanofi-Aventis, Bangladesh


  • Geniol
    GlaxoSmithKline, Argentina


  • GIB ASS
    GIB Pharma, Germany


  • Globoid
    Nycomed, Norway


  • Glyprin
    Upha, Singapore


  • Godamed
    Pfleger, Germany; Pfleger, Israel


  • Godamed (Acetylsalicylic Acid and Glycine)
    Pfleger, Germany


  • Golden-Udder (veterinary use)
    Shep-Fair, United Kingdom


  • Grippesin
    Biocrom, Argentina


  • Halfprin
    Kramer, United States


  • Hassapirin-Puro
    Mintlab, Chile


  • Heartcare Aspirin
    Brand Support, New Zealand


  • Herz ASS
    Gerot, Austria


  • Herz-Ass-Ratiopharm
    ratiopharm, Lithuania; ratiopharm, Luxembourg


  • HerzASS-ratiopharm
    Ratiopharm, Germany; Ratiopharm, Estonia; Ratiopharm, Luxembourg; Ratiopharm, Latvia


  • Herzschutz ASS ratiopharm
    Ratiopharm, Austria


  • Hjerdyl
    Sandoz, Denmark


  • Hjertemagnyl
    Nycomed, Denmark; Nycomed, Estonia


  • Hjertemin
    Medic, Denmark


  • Idotyl
    Ferrosan, Denmark


  • Ionil T
    Galderma, New Zealand; Galderma, Peru


  • Iskia
    Shiono Kemikaru, Japan


  • Istantal (Acetylsalicylic Acid and Ascorbic Acid)
    Unifarm, Italy


  • Jusprin
    Julphar, Bahrain; Julphar, Oman


  • Kalmaline (Acetylsalicylic Acid and Caffeine)
    Coup, Greece


  • Kalmodine (Acetylsalicylic Acid and Caffeine)
    Coup, Greece


  • Kalmol (Acetylsalicylic Acid and Caffeine)
    Specifar, Greece


  • Kalmopyrin
    Gedeon Richter, Hungary


  • Lo-Aspirin
    Be-Tabs Pharmaceuticals, South Africa


  • Lowasa
    Hospira, Ireland


  • Macrolvet (veterinary use)
    Divasa Farmavic de Portugal, Lda, Portugal


  • Magnaprin
    Rugby, United States


  • Magnecyl (veterinary use)
    McNeil, Sweden


  • Magnecyl brus
    McNeil, Sweden


  • Magnecyl-koffein brus (Acetylsalicylic Acid and Caffeine)
    McNeil, Sweden


  • Magnyl DAK
    Nycomed, Denmark


  • Magnyl SAD
    Amgros, Denmark


  • Magnyl
    Actavis, Iceland


  • Maximum Strength Aspro Clear
    Bayer, Malta


  • Mejoral Cafeina (Acetylsalicylic Acid and Caffeine)
    GlaxoSmithKline Consumer Healthcare, Spain


  • Mejoral Descaf.
    Farpasa, Peru


  • Mejoral NF (Acetylsalicylic Acid and Caffeine)
    Farpasa, Peru


  • Melhoral Infantil
    GlaxoSmithKline, Portugal


  • Metaspirine (Acetylsalicylic Acid and Caffeine)
    Glaxo Wellcome, France


  • Meted
    Alliance, Ireland


  • Methocarbamol and Aspirin (Acetylsalicylic Acid and Methocarbamol)
    Stevens, United States


  • Methoxisal (Acetylsalicylic Acid and Methocarbamol)
    Rougier, Canada


  • Micropirin
    Dexcel, United Kingdom; Dexcel, Israel


  • Midol
    Hemofarm, Serbia


  • Migpriv (Acetylsalicylic Acid and Metoclopramide)
    Sanofi-Aventis, Belgium


  • Migrafin (Acetylsalicylic Acid and Metoclopramide)
    Combiphar, Netherlands; Delphi, Netherlands; Dr. Fisher, Netherlands; EU-Pharma, Netherlands; Euro, Netherlands; Sanofi-Aventis, Netherlands


  • Migraspirina
    Bayer, Portugal


  • Miniasal
    Nycomed, Germany


  • Miniaspi 80
    Mersifarma, Indonesia


  • Minigrip (Acetylsalicylic Acid and Glycine)
    Kalbe, Indonesia


  • Mioasa
    Cheminter, Guatemala


  • Monospirin
    Ziska, Bangladesh


  • Naspro
    Nicholas, Indonesia


  • Neoacetilsalicilo rugistis
    Sanitas, Lithuania


  • Neospin
    Edruc, Bangladesh


  • Nichiaspirin
    Nichi-Iko PharmaceuticalJMA, Japan


  • Nipas
    Galena, Poland


  • Nitogis
    Shiono Kemikaru, Japan


  • Norwich
    Chattem, United States


  • Nötras
    Liba, Turkey


  • Novosta (Acetylsalicylic Acid and Pravastatin)
    Novell, Indonesia


  • Nuevapina
    Fabop, Argentina


  • Nu-Seals
    Alliance, United Kingdom; Alliance, Ireland; Lilly, Kenya; Lilly, Tanzania; Lilly, Uganda; Phadisco, Malta


  • Okal (Acetylsalicylic Acid and Glycine)
    Puerto Galiano, Spain


  • Opeaspirin
    O.P.V., Vietnam


  • Opon
    Gripin, Turkey


  • Percodan (Acetylsalicylic Acid and Oxycodone)
    Bristol-Myers Squibb, Canada; Endo, United States


  • Pharmaspirin
    Sodhan, Turkey


  • Piremix (veterinary use)
    Nuova ICC, Italy


  • Piricard
    Dr. Collado, Dominican Republic


  • Pluspiryna (Acetylsalicylic Acid and Caffeine)
    Polpharma, Poland


  • PMS-ASA
    Pharmascience, Canada


  • Polfungicid (Acetylsalicylic Acid and Chlormidazole)
    ICN, Poland


  • Polocard
    Polpharma, Poland


  • Polopiryna C (Acetylsalicylic Acid and Ascorbic Acid)
    Polpharma, Poland


  • Polopiryna S
    Polpharma, Poland


  • Polopiryna
    Polpharma, Poland


  • Posafilin (Acetylsalicylic Acid and Podophyllotoxin)
    Healthcare Logistics, New Zealand


  • Primaspan
    Orion, Finland


  • Proficar
    Polfarmex, Poland


  • Proxime (Acetylsalicylic Acid and Glycine)
    Sanbe, Indonesia


  • ratio-Oxycodan (Acetylsalicylic Acid and Oxycodone)
    ratiopharm, Canada


  • Remin
    Arab Pharmaceutical Manufacturing Co. LTD. - APM, Oman


  • Resprin
    Ricesteele, Ireland


  • Restor
    Sandoz, Indonesia


  • Rheumatine (veterinary use)